Do low-discrepancy sequences work in discrete spaces?

Low-discrepancy sequences in a real space ($[0,1]^n$) seem like a really excellent tool for evenly sampling a sample space. As far as I can tell, they generalise well to any real space, if you use an appropriate map (eg. $[0,1]\to[a,b]$ linear map).

Do such sequences generalise to discrete spaces? eg. if I have a space that has only two elements in each dimension (eg. boolean switches), can I just map $[0,0.5]\to 0;\ (0.5,1]\to 1$? What about for dimensions with more elements (eg. a 4-state switch?). And for spaces with different number of states in each dimension?

My intuition says that this might work ok, especially if the sub sequence is longish, but that it might work better for some sequences than for others, depending on the number of states (eg. a Halton sequence might have odd interactions with a dimension with a prime number of states, or a Sobol' sequence might only work for dimensions with $2^n$ elements). But I have done no testing.

If this doesn't work, why not?

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If you have a finite number of spaces, you will be better off with an explicit enumeration of possible spaces with a balanced incomplete block design built upon them. In the end, the properties of the low discrepancy sequences are asymptotic, with desirable properties achieved with the lengths of the order $N\sim 6^s$ where $s$ is the dimension of your space. If the number of possible combinations is less than that, you can just take all possible combination and achieve a balanced design with that.

Update: there was a book that discussed using QMC for Poisson processes and Bernoulli trials. May be you'd find something useful there, although in my opinion it is a very far cry from a good value for the money. For \$15, maybe. I found it to be somewhat sloppy in places, pushing the author's (sometimes weird) ideas rather than utilizing what's been understood as the best methods in the literature.

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Nice general answer, Stask, but it only really addresses the assumptions behind my question, and not my question directly. Thanks for pointing out BIDB, but I still would like to know if low-discrepancy sequences would work the way I'm describing (this may just be a matter of clarification around what you mean by "the properties ... are asymptotic). –  naught101 May 2 '12 at 6:05
A separate question: how is BIDB different to orthogonal latin hypercubes? Seems like basically the same thing (although perhaps coming from different angles). Also, what is QMC? –  naught101 May 2 '12 at 6:06