# Comparing proportions from the same sample of patients

The question I have is how to test if two proportions from the same sample of patients are significantly different from each other, indicated by a p-value?

Example: 100 people, 1 has Disease A and 2 have Disease B. Is the occurrence of Disease A more frequent than Disease B, ie. occurrence of Disease A given by 1/100 compared to 2/100 for B?

Keyword is 'same' sample of patients. Any help would be much appreciated. :)

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Can the same patient have both diseases? –  Michael Chernick Aug 16 '12 at 11:24
Since these samples are the same standard inference assuming independent random samples form a given population is violated. What is the inference that you want to make? Are you wanting to test whether or not the data indicate that the incidence for B is greater than for A in the population that the 100 patients were sampled from? –  Michael Chernick Aug 16 '12 at 11:32
@Michael Chernick: yes patient can have both diseases.I do want to test whether or not the data indicate that the incidence for B is greater than for A in the population that the 100 patients were sampled from –  bioinformant Aug 16 '12 at 11:42