How to draw funnel plot using ggplot2 in R?

Question

As title, I need to draw something like this:

Can ggplot, or other packages if ggplot is not capable, be used to draw something like this?

Answer 1

Although there's room for improvement, here is a small attempt with simulated (heteroscedastic) data:

library(ggplot2)
set.seed(101)
x <- runif(100, min=1, max=10)
y <- rnorm(length(x), mean=5, sd=0.1*x)
df <- data.frame(x=x*70, y=y)
m <- lm(y ~ x, data=df) 
fit95 <- predict(m, interval="conf", level=.95)
fit99 <- predict(m, interval="conf", level=.999)
df <- cbind.data.frame(df, 
                       lwr95=fit95[,"lwr"],  upr95=fit95[,"upr"],     
                       lwr99=fit99[,"lwr"],  upr99=fit99[,"upr"])

p <- ggplot(df, aes(x, y)) 
p + geom_point() + 
    geom_smooth(method="lm", colour="black", lwd=1.1, se=FALSE) + 
    geom_line(aes(y = upr95), color="black", linetype=2) + 
    geom_line(aes(y = lwr95), color="black", linetype=2) +
    geom_line(aes(y = upr99), color="red", linetype=3) + 
    geom_line(aes(y = lwr99), color="red", linetype=3)  + 
    annotate("text", 100, 6.5, label="95% limit", colour="black", 
             size=3, hjust=0) +
    annotate("text", 100, 6.4, label="99.9% limit", colour="red", 
             size=3, hjust=0) +
    labs(x="No. admissions...", y="Percentage of patients...") +    
    theme_bw() 

Answer 2

If you are looking for this (meta-analysis) type of funnel plot, then the following might be a starting point:

library(ggplot2)

set.seed(1)
p <- runif(100)
number <- sample(1:1000, 100, replace = TRUE)
p.se <- sqrt((p*(1-p)) / (number))
df <- data.frame(p, number, p.se)

## common effect (fixed effect model)
p.fem <- weighted.mean(p, 1/p.se^2)

## lower and upper limits for 95% and 99.9% CI, based on FEM estimator
number.seq <- seq(0.001, max(number), 0.1)
number.ll95 <- p.fem - 1.96 * sqrt((p.fem*(1-p.fem)) / (number.seq)) 
number.ul95 <- p.fem + 1.96 * sqrt((p.fem*(1-p.fem)) / (number.seq)) 
number.ll999 <- p.fem - 3.29 * sqrt((p.fem*(1-p.fem)) / (number.seq)) 
number.ul999 <- p.fem + 3.29 * sqrt((p.fem*(1-p.fem)) / (number.seq)) 
dfCI <- data.frame(number.ll95, number.ul95, number.ll999, number.ul999, number.seq, p.fem)

## draw plot
fp <- ggplot(aes(x = number, y = p), data = df) +
    geom_point(shape = 1) +
    geom_line(aes(x = number.seq, y = number.ll95), data = dfCI) +
    geom_line(aes(x = number.seq, y = number.ul95), data = dfCI) +
    geom_line(aes(x = number.seq, y = number.ll999), linetype = "dashed", data = dfCI) +
    geom_line(aes(x = number.seq, y = number.ul999), linetype = "dashed", data = dfCI) +
    geom_hline(aes(yintercept = p.fem), data = dfCI) +
    scale_y_continuous(limits = c(0,1.1)) +
  xlab("number") + ylab("p") + theme_bw() 
fp