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Interpreting negative binomial regression with log transformed independent variables

My independent variables were highly skewed, so to normalise the distribution they were log transformed. Also since there were zeros in the data, I've added + 1 to transform the variables. This is ...
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0answers
26 views

Estimating mortality rates with direct age-standardization

I'm attempting to calculate the mortality rates of AMI (acute myocardial infarction) in patients (cases) with high bloodpressure, between the years 2001 to 2008. For every case I have 2 matched ...
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47 views

Interpretation of log transformed predictor in negative binomial regression

I mainly want to make sure that I'm making the correct interpretation here. I built a negative binomial regression model predicting a count variable. There was evidence of overdispersion or I would ...
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1answer
219 views

Calculate incidence rates using poisson model: relation to hazard ratio from Cox PH model

I want to calculate incidence rates to present along hazard ratio's in order to present both relative and absolute measures of risk. I saw in other studies that such incidence rates can be calculated ...
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0answers
11 views

Considering Age-standardized incidence rates: Will changing the reference population change the incidence rates

Im trying to calculate the mortality rates for males and females in two different disease groups (type 1 and type 2 diabetes). In my primary analyses i forgot to use respective gender as the ...
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2answers
166 views

Calculate confidence interval from point estimate and standard error

Im having a problem with calculating a confidence interval for an incidence rate ratio between two populations. Using PROC STDRATE from SAS, I've obtained the Incidence Rate Ratio (the difference in ...
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3answers
96 views

How to prove that one variable's change is influenced by another variable; that is to say, are they related?

I major in bioinformatics. We all know that temperature changes during a year. I find that a disease incidence is really high when temperature is relatively high, while it becomes really low when the ...
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0answers
22 views

Rolling twelve-month crime rate

I need to do a 12 month rolling crime rate. I have monthly crime counts and population counts every 3 months. For a calendar year I would usually use a population from mid-year as the denominator and ...
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2answers
357 views

Comparing the ratios of occurrences

I am trying to find a statistical test for comparing the ratios of occurrences and would appreciate any help. There are two groups; treatment and control. Each group has three categories of outcomes; ...
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2answers
238 views

Comparing multiple incidence rates

I asked the following question on stack overflow yesterday: Negative binomial function in R Reading comment 2, I understand that I cannot use a negative binomial modeling approach (a Poisson model ...
2
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0answers
75 views

How to calculate SE for the ratio of two proportions?

I have evaluated the prevalence (proportion) of a disease in men and women, in different studies available in the literature. So I have sample sizes for men and women (in different studies) and also ...
5
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1answer
273 views

Incidence Rate Ratio (IRR) in R from linear regression using log-transformed data?

I was wondering if it would make sense to calculate IRR for OLS (not poisson), but the OLS is done using log-transformed data? I have a set of crude death rate data (which I'm still debating whether ...
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1answer
141 views

Inverse Incidence Rate Ratio

I wondered if it is possible to calculate the inverse of an IRR like we can for odds ratio (inverse = 1/x). For example: IRR = 1.40, 95% CI = 1.18 -1.65 Inverse IRR: = 1/1.40 = 0.71 Thank you ...
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1answer
80 views

Simulation of woman's age of getting breast cancer (cumulative incidence rate)

I am writing a programme to simulate the age at which women will get breast cancer. I have data on the cumulative incidence rate for the whole population. What I am doing right now is using Monte ...
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1answer
262 views

Comparing Incidence Rate Ratios

I am trying to compare incidence rate ratios (IRR). This is what I have: Group A (exposed vs. unexposed) IRR and Group B (exposed vs. unexposed) IRR So how would I correctly test for the ...
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3answers
3k views

Comparing incidence rates

I want to compare to incidence rate's between two groups (one without a disease and one with). I was planning to calculate the incidence rate ratio (IRR), i.e. incidence rate group B/ incidence rate ...
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1answer
359 views

Negative binomial — IRR interpretation for predictors

I have a zero-inflated negative binomial model. I have used incidence rate ratios and I'm trying to interpret the coefficients in relation to my predictors. Most of my predictors are continuous ...
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1answer
325 views

Alternative name for “incidence rate ratio”

I'm using a negative binomial GLM to predict individual level scores on a psychometric test that ranges from 0-27 and presenting the coefficient "incidence rate ratios". It seems a little strange to ...