Meta-analysis refers to methods focused on contrasting and combining results from different studies, in the hope of identifying patterns among study results, sources of disagreement among those results, or other interesting relationships that may come to light in the context of multiple studies.

learn more… | top users | synonyms

1
vote
1answer
12 views

Test for homogeneity in meta-analysis with a large number of studies

So I am conducting some literature searches on behalf of someone. I stumbled across a meta-analysis which used 23 studies. It tested the homogeneity of the studies used, using what I think is a ...
1
vote
1answer
27 views

Separate levels of an outcome measure reported, but the means and SDs do not add up to the “total items,” why?

I am working on a meta-analysis that distinguishes achievement on two levels: content acquisition (e.g. knowledge and comprehension) and skills application (e.g. problem solving, etc.). I came across ...
0
votes
0answers
8 views

Outcome Results - Mean Change & Standard Error - Missing Standard Deviation

The results of a clinical trial are given as "Mean Change", together with a "Standard Error", also the "Mean Differences" of the Intervention and Control are given, together with 95% Confidence ...
1
vote
2answers
21 views

Dealing with studies with no cases in meta-analysis

I am meta-analysising the following data by age range: ...
0
votes
1answer
25 views

Comparing rates of success in paired groups of samples

I have $2n$ paired populations, on which I measure a rate of success, let's say $(r_{group}^i)_{group \in (0,1)}^{i \in[1,n]}$ where $r_0^i$ and $r_1^i$ are the rates of success in the $i$-th pair of ...
2
votes
0answers
25 views

multiple hypothesis correction for meta-analysis with missing p-values

I would like to combine multiple p-values (e.g., using Fisher or Stouffer), where some hypotheses may have missing p-values across studies. e.g., ...
0
votes
0answers
13 views

Comparing effect sizes of two treatments from a large number of studies

I suppose this would be some kind of meta-analysis. I would like to compare the effect sizes of two treatments from a large number of published studies. I would like to show that the other treatment ...
0
votes
1answer
24 views

Averaging effect sizes?

Suppose I need an estimate of effect size for a power analysis. I read the relevant literature and calculated Cohen's $d$ from some number (3) of studies. If the Cohen's $d$s are, for example, $d_{1} ...
2
votes
2answers
66 views

Change scores as outcome measurements in clinical trials

I am performing a Meta-Analysis about a mental disease, comparing intervention vs. control groups and try to extract outcome results from published study papers. In some clinical randomised trials ...
0
votes
0answers
46 views

Meta-Analysis Data Extraction Process - Reporting of Outcome Measures

I am conducting a Meta-Analysis of a clinical intervention in randomised trials. I am using the RevMan Software of the Cochrane Foundation. The problem regards the extraction process of relevant ...
5
votes
1answer
91 views

Torn between PET-PEESE and multilevel approaches to meta-analysis: is there a happy medium?

I am currently working on a meta-analysis, for which I need to analyze multiple effect sizes nested within samples. I am partial to Cheung's (2014) three-level meta-analysis approach to meta-analyzing ...
4
votes
1answer
51 views

Discrepancy between metafor and weighted lm() standard errors

My friend and I are trying to understand why a weighted lm() v. a fixed-effect rma model from the ...
1
vote
0answers
30 views

Heterogeneity measures when pooling meta-analyses: what assumptions do we make?

I am looking at the possibilities and limitations of meta-meta-analysis (MMA), put differently, pooling the results of multiple meta-analysis. I realise that it is better to include primary studies, ...
4
votes
1answer
78 views

Computing Paired Samples (pre/post) Effect Size with Limited Information

I'm conducting a meta-analysis using the Hedge's g effect size statistic. Many of the studies are only reporting: pre-treatment mean score pre-treatment standard deviation post-treatment mean score ...
1
vote
1answer
37 views
1
vote
0answers
20 views

Relation between variance stabilizing transformations and effect sizes?

When researching effect size for proportions, in particular the paper Effect-Size Indices for Dichotomized Outcomes in Meta-Analysis, that at least two of the usual effect sizes are realy variance ...
0
votes
1answer
41 views

Resources for understanding meta-regression?

I'd like to learn more about the statistical techniques that one should use for a meta-regression. I'm interested in both general theory, as well as examining methodologies in R.
1
vote
0answers
14 views

Meta analysis; significance test of correlations

I have performed a meta analysis using the 'Metafor' package in R. I have some corrected correlations. Now I am wondering how I can calculate whether they are significant and whether there is a ...
1
vote
0answers
23 views

Publication bias in meta-analysis of single observation studies

I have conducted a systematic review and lme model of 50 studies attempting to economically value ecological services (previously un-valued). These studies do not use data samples or observations, ...
2
votes
1answer
64 views

Calculating effect size (lnR) variances for studies with different study designs for use in meta-analysis

My question concerns the calculation of effect size variance for studies that are going to be included in a meta-analysis. I want to calculate variance so that I can weight each study by the inverse ...
1
vote
1answer
69 views

Meta-regression of utility weights (hierarchical linear model)

I would like to perform a meta-regression of utility weights for two health states (1st state - overall, with specific condition; the second - with additional conditions, comorbidities). Some ...
1
vote
0answers
41 views

Meta-analysis - Multiple Outcome measures for the same population

Basically, I am trying to include some binary data into a meta-analysis and not sure how to include this dataset. If you look at the attached table, each red square that i drew depicts an ...
2
votes
1answer
37 views

Hartung-Knapp CIs in meta-analysis with two trials

I'm having trouble convincing my collaborators that we should use the Hartung-Knapp correction when we have only two trials. This paper seems pretty convincing ...
2
votes
2answers
56 views

meta analysis of odds ratios

I would like to work on a meta analysis project, I have kept 8 studies that satisfy my criteria and I'd like to continue with these. Their results are formed as odds ratios (OR) and confidence ...
0
votes
0answers
29 views

Transformation of means and sd in meta-analysis

I am doing a meta-analysis based on the means and standard deviations collected from many other studies. The distribution of the data indicated that I need to transform the data. However, the authors ...
0
votes
0answers
27 views

Meta-analysis of skewed data with low event rate (single-arm studies)

I am trying to pool the data from several single-arm studies regarding the re-infection rate of a certain disease using STATA. From each study, I have obtained the no. of re-infections, and the ...
1
vote
1answer
97 views

Is it valid to use a generalized model with no replicates

I've got a designed experiment that is a long-term agricultural station. The field is divided into 11 rows and 6 columns (each column has two sub-columns). Each resulting plot represents a unique ...
1
vote
0answers
44 views

Meta-analysis: Difference between direct and indirect restriction of range

Looking at meta-analysis for personnel selection procedures, I am having really big troubles to figure out the difference between concepts of direct restriction of range (DRR) and indirect restriction ...
3
votes
1answer
61 views

Metafor package in R: Ranktest for multivariate meta analysis

I have done a multivariate meta analysis with R, with support from metafor package. I am using rma.mv-method which gives an R object of class c("rma.mv","rma"). My question is about looking for funnel ...
2
votes
1answer
112 views

R-Metafor: Meta-analysis and mixed effect model

This is an example of my dataset ...
0
votes
0answers
35 views

What are the quantitative methods alternative to Meta-Analysis?

What are the alternative statistical quantitative synthesis methods for combining studies, if we can't apply meta-analysis because of the heteronegeity or the shape of the data, for the data set of ...
0
votes
0answers
52 views

Which method should I use to combine the data of my studies?

I want to make a meta-analysis on household consumption expenditures elasticity data. In these studies that I've got; methods and regions and etc. varies according to studies. But at last, the results ...
1
vote
0answers
52 views

Meta analysis of multiple-treatment-multiple-endpoint studies

I have read some things about Meta Analyses for stochastically dependent effect size (e.g. Gleser and Olkin (2009) in The handbook of research synthesis and meta-analysis (2nd ed.). I understood ...
2
votes
0answers
25 views

Alternatives to Fisher's method?

I'm using the Mann-Whitney U test to compare scores from a foreground (n ranging between 5-500) to a large background (up to 2000). Since my foreground is quite small I've been taking smaller random ...
4
votes
1answer
39 views

Estimate an overall correlation from the correlations within subgroups

Assume that you are working with variables $x$ and $y$ divided into groups two groups, $g_1$ and $g_2$. You know the following information: The number of people within groups $g_1$ and $g_2$, ...
3
votes
1answer
53 views

User weights in metafor

While reading "Conducting Meta-Analyses in R with the metafor Package" (http://www.jstatsoft.org/v36/i03/paper), I am wondering how model fitting works with user defined weights. In chapter 2.4 is ...
2
votes
1answer
72 views

Converting Adjusted Odds Ratios to its RR counterpart

I am doing a meta-analysis of studies which reported their estimates sometimes as OR and sometimes as RR. I wanted to convert the OR to RR, so that I can pool them together. I know that I can use this ...
2
votes
1answer
81 views

Calculating heterogeneity (Cochrane Q and I^2 statistics) in random effect model

I want to ask whether I can calculate the Cochrane Q statistics and I^2 statistics in random effect model. I collected some data from different areas and want to compare the prevalence of allergic ...
2
votes
0answers
80 views

Convert hazards ratio to odds ratio

In meta-analysis: How do we convert hazard ratios in some studies to odds ratio? There are case control and cohort studies to be included and some of them report hazard ratios. The raw data is not ...
0
votes
0answers
44 views

Meta-analysis with a categorical explanatory variable

I am attempting to fit a model to my data for meta-analysis I'm working on. The data is structured as follows: ...
0
votes
0answers
34 views

Meta analysis on multiple endpoints and unknown covariance

I am doing meta-analysis on intervention studies on human subjects where a number of measures were obtained before and after the intervention in a treatment and a control group. We categorize the ...
3
votes
1answer
93 views

Is stratified meta-analysis more or less objective than meta-regression?

Reviewer asked me why I use meta-regression as a way how to deal with heterogeneity among effect sizes instead of conducting stratified meta-analysis. I tried to google "stratified meta-analysis" and ...
0
votes
0answers
49 views

Difference in proportion: Pre-post intervention-control study design

I am conducting a meta-analysis where I want to compare the proportion of samples pre- vs post- intervention. To do this, I have been calculating the difference in proportion (Post - Pre) as the ...
0
votes
0answers
103 views

Meta-analysis of percentages at baseline and follow-ups in R using metafor package

I would like to conduct a meta-analysis in the context where I have studies available that measure a continuos variable at multiple time points (0, 1, 2, 3, 4, 5). Time 0 represents the baseline where ...
0
votes
0answers
33 views

meta-analysis, effect sizes for standard deviations

Is there any possibility to calculate effect sizes for the differences of standard deviations of two groups? (Is there any possibility to calculate the difference in the standard deviation between two ...
1
vote
0answers
31 views

Mixing ITT and TOT/LATE Effect Sizes in Meta-Analysis

I have a question concerning the coding of Effect Sizes for a large (educational) Meta Analysis with mostly latent outcome variables. Some studies provide "Intent to Treat" Data from which I ...
1
vote
0answers
13 views

Multiple groups - how to regularise estimate of level 1 parameters based on level 2

I am fitting some relatively complex structural equation models, but the specific model is not so important. I am estimating multigroup models, such that one parameter is completely free across ...
1
vote
1answer
31 views

Meta-analysis with studies reporting both positive and negative estimates

I'm organizing a meta-analysis on performances with studies showing sometime positive and sometime negative estimates. Sometime the result of the study is in a positive direction, with higher scores ...
0
votes
1answer
38 views

How do I translate logistic regression output into logged OR (and SE) for meta-analysis?

I'm attempting to conduct a meta-analysis using (logged) odds ratios, I'm using the Generic Inverse variance method (Review Manager) as some of my studies only report odds ratios and CIs (not raw ...
4
votes
1answer
82 views

Interaction effect of 2x2 ANOVA in meta-analysis

I want to meta-analyze the interaction effect of a 2x2 ANOVA. (I am not talking about an interaction in the meta-regression, as in this question but about an interaction as the focal effect that ...