Meta-analysis refers to methods focused on contrasting and combining results from different studies, in the hope of identifying patterns among study results, sources of disagreement among those results, or other interesting relationships that may come to light in the context of multiple studies.

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Testing 3-way interaction of categorical variables in a meta analysis in R

I'm currently working on a meta-analysis using the metafor package for R. I have several categorical moderators, a few of which are multi-category, that I'm including in the analyses. When using one ...
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9 views

Techniques or resources about analyzing published studies data

Excluding meta-analysis, are there any technique or resources which discuss the analysis of published data? The second part of this paper could be a small lead to what i'm talking about PS i'm ...
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17 views

Meta-analysis on positively transformed effect sizes

I want to assess whether or not a wide range of animal behaviours in experimental studies change from control responses. As such, I want to compare absolute changes, rather than increases (+) or ...
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1answer
40 views

Metafor package in R: meta regression and scatter plot

I am doing a meta-regression with metafor package in R. The mixed-effect model for proportion is used to assess the linearity between study performed year and medication prevalence. Here below is my ...
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1answer
26 views

Are there any scientific journals about meta-analysis?

I'm searching about scientific journals which are oriented only about meta-analysis. I knew there were some but i can't find any both searching google and http://www.scimagojr.com/journalrank.php Are ...
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14 views

Averaging and comparing mean values across studies

I am having a statistical problem that falls into two parts: (!) I have several literature reports on studies that have investigated the effect of drug "A" on a particular laboratory parameter. Some ...
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1answer
26 views

Metaanalysis - how big should be the ICC (Intracluster correlation coefficient)?

The background is a metaanalysis of cluster randomised clinical studies. The included studies report no ICC for final values, the chosen ICC for the calculations was 0,02. Similar studies in the same ...
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2answers
63 views

Meta analysis across studies with multiple response measures

I'm trying to do a meta analysis across a bunch of bird playback studies. Thanks to help on a previous post here I'm fairly certain I need to use inverse variance weighting (maybe with the 'meta' ...
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18 views

Combining two different sampling methods

Let's say I want to quantify the preference that people have towards shoe color as a function of their age. For simplicity, assume there are only black, gray, and brown shoes. First I ask 1,000 ...
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1answer
30 views

Effects in metaanalysis forest plots - what are the conclusions?

In metaanalysis results are often reported in forest plots, where multiple studies are included. Different, continuous outcome scales are used to measure the effect of a treatment on the course of a ...
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2answers
48 views

Minimal requirements for funnel plots?

Are there basic minimum requirements for funnel plots to be valid or having a sufficient quality to assess publication bias? For example in regard to: Numbers of included studies? Size of ...
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10 views

How to avoid a high familywise error rate in case i can't favor between tests?

If i can't favor between tests , what should i do to avoid high familywise error rate. For example, I am doing a meta-analysis i believe that some variables might explain the heterogeneity like Year ...
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1answer
32 views

Reporting of Heterogeneity in Metaanalysis

The background is a forest plot of a meta-analysis which is reported to have been calculated with a "random effects model". The pooled effect is reported as a standardized mean difference (SMD). ...
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30 views

How can I conduct meta-regression on prevalence meta-analysis?

After searching,I didn't find any guidelines on conducting meta-regression on prevalence meta-analysis(no treatment group). Where or how can i make it? here is a data set, after i made an overall ...
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1answer
21 views

Is there anyway, we can convert Rate ratio to Odds ratio

I am doing a meta-analysis of longitudinal data in which few studies have OR as summary estimate while others have rate ratio (incidence). Except for the summary estimate, there is no heterogeneity ...
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1answer
22 views

Effect size (cohen's d) when mean and SD are zero

I am calculating effect sizes (Cohen's d) for a meta-analysis to examine pre-test to post-test differences after receiving a word-learning treatment. I am using pre-test and post-test means and SDs in ...
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3answers
40 views

Is there an effect size for a single proportion?

I want to conduct a meta analysis of the incidence rate of the complications of a specific disease. Studies report these complications as 4 patients died or 2% died. And there are no comparable ...
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1answer
31 views

Calculate confidence interval for hazard ratio given maximum likelihood and standard error

I'm doing a meta-analysis and one of the studies presents the hazard ratio (HR) with the maximum likelihood estimate (MLE) with its standard error (SE). The rest of the studies give the HR and the ...
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1answer
21 views

Conducting a comparative analysis with studies that use different response measures

I want to conduct a comparative analysis using bird playback studies. Unfortunately, many of these studies use different response measures (closest approach to the speaker, time spent near the ...
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3answers
47 views

Funnel Plot Question

Hopefully someone can assist a bit, I just came across a funnel plot that I can not interpret. I have a feeling it is due to the high heterogeneity in the Meta-analysis. (I2= 92%) Basically, this was ...
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57 views

Meta-analysis using experimental reliability data

I have a rather conceptual question. We measured experimentally the reliability of a certain readout. Now what I would like to do is to use this data to give a statement about the results of previous ...
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1answer
27 views

What is a credibility value in meta-analyses?

I came across the term credibility value in reference to meta-analytic analyses and am not familiar with it. It is similar to a credibility interval? Here is the context: "Because there is more ...
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1answer
31 views

Interpreting intercept-only meta-analysis model when effect size is raw mean

Although I plan to use moderators to understand how the raw mean (and its sampling variance) is related to specific experimental conditions, I am curious: how would you interpret the intercept-only ...
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1answer
48 views

Is it possible to compute some measure of effect size from four means from a split-plot (both within- and between-subjects) 2x2 design?

For a meta-analysis, we are interested in the comparison of two groups. From the articles, we can extract four means: two baseline measures on one of our dependent variables, and two measures ...
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1answer
46 views

Meta Analysis - Importance of significance levels of included studies

How important should the significance level be in the decision process to include single results in a Meta-Analysis? In a Meta-Analysis of different studies some of the included studies describe ...
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2answers
52 views

meta-analysis of p values

I am a bit confused about doing the meta analysis with my data. Given z-scores I calculate p values in a way: p.values = 2*pnorm(-abs(z)). Then I would like to ...
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1answer
15 views

How to compute standard error of the log-hazard in the baseline arm from an n-arm study

I'm trying to use GeMTC (a package for Bayesian Network Meta Analysis) for an analysis that mixes contrast-based data (Hazard Ratio;HR) with arm-based data (event counts). The documentation specifies ...
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2answers
87 views

How does one run a meta-analysis on indirect / mediated effects?

I have two different datasets, and am reporting the same mediation analysis in both. The mediation in one study is clear, in the other less so. I am trying to run a small meta-analysis across both ...
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1answer
38 views

computing heterogeneity assigned to random factors in meta-analysis

I want to calculate the proportion of total variance in a multi-level meta-analysis with 2+ random effect terms according to pp. 1261 & equation (24) in Nakagawa & Santos 2012 ...
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38 views

meta-analysis with interaction factors and continuous variable {metafor}

When you have two factors A (levels: A1, A2) and B (levels: B1, B2) with their interaction, R {metafor} package allows you to ...
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1answer
35 views

Correlational meta-analysis and moderators

I have 3 correlations between A and B through 3 different studies : ...
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1answer
10 views

Quality assessment scale for pre clinical study

I'm planning a systematic review investigating the mean value of a parameter in the population. The ideal study in my review would be a study where given a variable sample size the investigator ...
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1answer
17 views

Approximating OR with RRR in meta-analysis

Similarly as in this question, I'm working with meta-analysis of studies reporting ORs of an event. I have one study where I'm not sure if it should be excluded. The frequencies of the outcome are: ...
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1answer
65 views

Import external correlation matrix and sample size to run (MA)SEM in Stata

I want to run a meta-analytic structural equation model (MASEM) in Stata. I already have the meta-analytic mean correlation matrix and the sample size for each correlation. Now I want to import this ...
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86 views

Meta-regression analysis: Residual heterogeneity larger than overall heterogeneity

I am estimating a mixed effects meta-regression model in R. The random effects have a multilevel structure (which reflects the studies from which the primary estimates were taken). The reported ...
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39 views

How to cluster/analyze effect sizes after meta-analysis? (meta-meta-analysis)

For a research project I compared persons with and without a specific disorder on basically every published outcome I could find. The idea was to get some sort of profile of this disorder (i.e. skills ...
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8 views

How can I complete a relative-risk meta-analysis with a different number of groups in the experimental and control arms?

I am conducting a meta-analysis using a statistical program. I need to compare 12 studies which evaluated an experimental condition with 20 studies that evaluated a control condition. What is the ...
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1answer
34 views

Correcting For Reliability/Consistency of a Measure in Meta Analysis (Cronbach's Alpha / Test Re-Test)

Is it good practice to correct for reliability of your measure in a meta analysis? This is what is suggested by Hunter and Schmidt (2004), but it seems weird to me to calculate your average effect for ...
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1answer
55 views

Meta-analysis and meta-regression results don't agree

In the context of a (multilevel) meta-analysis, I want to caluclate grand effect size estimates for subsets of data corresponding to the levels of a categorical variable. Using the example below, I'd ...
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16 views

Ratio of two numbers for meta-analysis

I would like to conduct a meta-analysis of ratios from several studies. That is, a meta-analysis using studies that report on counts for two syndromes (i.e., epiglottitis and sepsis due to a ...
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1answer
36 views

Post hoc analysis after meta regression

I am running a meta-analysis using metafor R package. I am comparing studies on a continuous variable, that can be synthetized by the mean. Such studies can be grouped in three blocks. I used a meta ...
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24 views

Can last observation carried forward (LOCF) be used in a meta analysis?

In an article I am reviewing, the authors used LOCF for missing data. In ordinary studies, I would frown on this and suggest multiple imputation. However, this study was a meta-analysis. Is LOCF an ...
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14 views

Question regarding simple meta-analysis of study location

I have what I believe to be a hopefully simple question. I am writing a systematic review of a pollination methodology. I am interested in comparing the amount of pollen collected among the different ...
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29 views

Can a meta analysis of continuous data be performed if data is only presented with mean values and interquartile ranges?

I am trying to do meta analysis of papers for a literature review. In some outcome data I have for continuous outcomes, the authors have only presented results as means with interquartile ranges. I am ...
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20 views

Meta-analys of GWAS and interpretation of estimated p-values

I'm a bit confused about a meta-analysis performed with PLINK on two studies. The statistics look like this for a specific SNP in each study: Study_1: OR = 3.657, SE = 0.336, p= 0.0001137 Study_2: ...
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57 views

Which method to be used to analyze this data?

You are building a model to predict disease risk from patient measurements such as age, blood pressure, family history, etc. You suspect that some features will have a non-linear effect: for example ...
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21 views

Meta analysis for regressions from ONE study in R?

I have ten regression analyses of the following form: $Y = b_0 + b_1 X_1 + b_2 X_2 + b_3 X_1 X_2$ All are from one sample/study. Each of them uses combinations of two of the Big Five domains. ...
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1answer
83 views

Combining multiple outcomes in studies (no meta-analysis)

I'm looking for a way to combine effect sizes (mean difference) and variances for several single studies but I don't want to conduct an overall meta-analysis. That means I'm only looking for an ...
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8 views

Metanalysis of normalized mean values - How to normalized the standard deviation

This is my first question here so I am not sure if will frame it correctly. I am trying to do a simple metanalysis of raw means comparing a psychological assessment (i.e. depression level) in two time ...
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41 views

meta-analysis of means and standard deviations

I am doing meta-analysis study on a parameter X measured in in the fed and fasted states. Studies are reporting mean and SD for the parameter. I need to come up with a meta value (and SD) for the ...