Tagged Questions
3
votes
2answers
204 views
What is the equation for combining standardized mean differences across multiple studies?
I am trying to come up with a combined/pooled standardized mean difference for meta-analysis of a dozen or so studies that have the same binary predictive groups and the same continuous outcome ...
3
votes
2answers
309 views
How to correct for inter-experimental variation in cell culture research?
I am testing cell cultures. I grow cells in a "control media" for 2 weeks. During these 2 weeks, the cells produce an antibody, and at the end of the 2 weeks, I measure the levels of the antibody. ...
0
votes
0answers
99 views
Meta-analysis using GWAS datasets of different diseases
It is well known that in Meta-analysis of Genome-wide association studies (GWAS) we combine the results of independent studies to get a pooled effect estimates (Odd ratios or betas) in order to ...
1
vote
2answers
169 views
Calculating standard error for funnel plots
I'm a programmer, with a decent but not-expert knowledge of stats, and I'm working through these instructions for how to create funnel plots.
I know that there are better ready-made tools (e.g. R) ...
3
votes
1answer
300 views
Standard error from OR and HR
I'm planning to combine several observational studies, some of which have produced odds ratios and some hazard ratios. How do I get the standard error from the odds ratio $1.57$ ($95\%$ CI: ...
2
votes
1answer
330 views
Alternative Egger's test, without using standard error
A simplified regression equation $ES=\frac{a+b}{n_1+n_2}$ has been suggested as an alternative to Egger's regression equation $\frac{ES}{SE}=\frac{a+b}{SE}$, where ES=Effect Size, $n_1$=sample size of ...
6
votes
1answer
440 views
Alternative funnel plot, without using standard error (SE)
Before submission of my meta-analysis I want to make a funnel plot to test for heterogeneity and publication bias. I have the pooled effect size and the effect sizes from each study, that take values ...
