I have 2 studies looking at the patient response to the same drug. Study 1 found 10,000 genes expressed above the background and 500 of them are differentially expressed and referred to as the drug ...
I am looking at the effect of genotype on a continuous variable. In total 16 comparisons were done involving 9 different SNPs. The number of significant events was 3 out of 16 tests (Mann-Whitney ...
I have conducted a search for genetic interactions using a simple dosage model: Y ~ A + B + AB where Y is the phenotype, in this case, gene expression values and A and B are vectors of genotype ...
I want to discover which genes are expressed in only one of five treatments. This is my pipeline: ANOVA between the five treatments Holm multiple testing correction Tukey for significant genes ...
Let's say that there is a table like the one below, where for each mutant (A, B, C, etc.) protein or peptide we have a binding and a functional information (true/false) column, and for each amino acid ...
I have p values from a lot of tests and would like to know whether there is actually something significant after correcting for multiple testing. The complication: my tests are not independent. The ...