# Tagged Questions

26 views

### Specifying contrasts for lme in 3x3 repeated-measures design

I would like to test the effects of two categorical variables, each with 3 levels, on some continuous data. Three groups of participants completed the same task for 3 types of stimuli, so it's a 3x3 ...
43 views

### Repeated measurement analysis advice in R lme and / or aov and a couple of more questions

I want to analyse the visual performance, operationalized via contrast threshold, depending on adaptation luminance and spectrum, gathered for 29 subjects. I'm currently kind of confused of how to do ...
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### Correlation assumption of Hochberg procedure in repeated measures design

I'm running a 3-factor (Between by Between by Within) ANOVA with the correlation structure modeled using a Random Intercept and Gaussian Serial Correlation. I have the following variables: Dependent ...
363 views

### Repeated measures over time with small $n$

I was given data to analyze for a study looking at the effects of a treatment on iron levels at four different time points (before treatment, the day treatment ended, 4 weeks after treatment, and 2-4 ...
102 views

### A mixed-effects model for repeated measurements vs multiple time point-wise comparisons with a simpler test

I have a pretty standard situation of a study in which repeated measurements are taken from the same individuals. There are two factors: "Group" (with 25 individuals in each of two groups) and "Day" ...
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### Is repeated measures ANOVA the right test?

I am studying a parameter in several organs of mice and I have two categorial factors. I would like to study the effects of those two factors on my parameter in each organ (I don't care about ...
442 views

### Is it necessary to correct alpha in repeated measures ANOVA before any post-hoc comparisons?

I have a cross-over design where a sample of subjects undergoes 7 different interventions, and within each intervention there are 3 time points (pre-intervention, post-intervention1, ...
160 views

### Survival analysis w/ repeated observations of experimental and control units within periods of differing size & trends over the periods

I have an experiment called Fear Conditioning Acquisition Protocol. We expose mice to subsequent white sounds followed by short electric shocks through the floor. Our aim is to let them learn to ...
185 views

### Repeated measurements with missing values

The data is measured in two biological replicates with two technical replicates, each. Each variable might be detected only in one or more replicates, in the others it is considered missing at ...
165 views

### Mixed model in R with paired design and covariates

I make habitat suitability models for animal species. The purpose of my research is to investigate the accuracy of different models. I clearly have a nested design: accuracy_measure -> response ...
120 views

### What would be a good paper to cite to explain simulation methods in proc mixed in SAS?

In order to analyze data obtained from a repeated measure study, I used the following SAS code: ...
2k views

### Bonferroni and Greenhouse-Geisser corrections with repeated-measures ANOVA

I guess my question comes in two parts: Following a 1x7 repeated-measures ANOVA, I carried out 3 pre-planned tests. Two were t-tests between 2 of the conditions. The third is a 1x6 ANOVA (to test ...
162 views

### How to examine effect of time over four time points across two experimental conditions?

My experiment entails comparing a mock-infected group with a virus-infected group across 4 different time points (3,5,8,10 weeks) looking at the proportion of immune cells. I have already compared ...
268 views

### What article or book clearly states that one can't use protected t-tests in within subjects ANOVA?

I have been asked to use protected paired samples t-tests in an analysis. The requester states that if I do not use the overall MSe from my (1 factor with four levels) within-subjects ANOVA when ...
863 views

### Correcting for multiple comparisons in a within subjects / repeated measures ANOVA; excessively conservative?

It strikes me that the available corrections for multiple comparisons in the context of a repeated measures ANOVA are excessively conservative. Is this actually the case? If so, what are some ...
647 views

### Can I have an example of pairwise comparisons of data against a within-subject factor?

Here is an ANOVA model with one between-subject factor (condition; 4 levels) and one within-subject factor (trial_seq; 20 levels). ...
1k views

### If a statistics doesn't reveal a significance do I have to calculate power for it?

Following the design and data described in this question, I did a simple one-way within-subjects repeated-measures (RM) ANOVA and found some significant p-values. I then applied non-orthogonal ...
253 views

### Mouse models - 'replicates' and analysis

I'm hoping to hear from someone who has worked on mouse models or similar biological analyses where there is a tendency to run 'replicates' of an experiment. I know multiple testing is a sizeable ...