# Tagged Questions

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### review papers on P-values, adjusted P-values and common statistical tests in bioinformatics

I'm looking for review papers which give comprehensive reviews of P-values, adjusted P-values and common statistical tests in bioinformatics.
2answers
91 views

### Significance of dummy variables in regression

I am using categorical variable (having three categories) as independent variable in model and found that one category is coming to be significant while another category is not coming to be ...
2answers
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### Three important issues

I don't understand three important issues : (1) Why do we calculate the test statistic under the null hypothesis ? (2) Why do we reject the null hypothesis when : p-value < significance level ? ...
0answers
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### Calculate p values based on differences between bootstrapped 95% confidence intervals

I have bootstrapped model fits to some data from different three groups, using the $2.5$ and $97.5$ percentiles to generate a $95\%$ confidence interval. I know that if $95\%$ confidence intervals do ...
2answers
97 views

### Combining p-values from different statistical tests applied on the same data

Although the title of the question appears trivial, I would like to explain that it is not that trivial in the sense that it's different from the question of applying the same statistical test in ...
0answers
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### Bootstrapping regression slopes - p-value and significance level

I have a data set showing an (exponential) increase in the size of an animal population over time. I can fit an exponential model to these data and obtain an estimate of the population growth rate ...
1answer
145 views

### When does it make sense to reject/accept an hypothesis?

In To P or not to P: on the evidential nature of P-values and their place in scientic inference, Michael Lew has shown that, at least for the t-test, the one-sided p-value and sample size can be ...
1answer
64 views

### Statistical significance in canonical correlation analysis

I do canonical correlation analysis between two multivariate datasets $X$ and $Y$. For each pair of canonical variates (x-y pair) I get the canonical correlation coefficient. How can I test its ...
1answer
54 views

### Relationship between test stat and p-value in relation to t-test

I was wondering why it is necessarily true that if a test statistic exceeds the critical value of t, then it will also be true that the p-value will not exceed the level of signi ficance.
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40 views

### P value for bootstrapping two means in laymen's terms

I've bootstrapped two means - each sample had 10,000 observations so I resampled each mean with replacement of 10,000 numbers from each sample. I did this over 50,000 iterations I've plotted the ...
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### Statistical significance problem

I've got an algorithm which assigns a score to a list of individuals (nodes). I want to discover which nodes received a statistically significant score. So I "randomized" the algorithm in order to ...
1answer
54 views

### Statistical Significance of Experiment

Two Groups, A & B, undergo same intervention. Group A (n=20). Group B (n=10). The only outcomes are symptomatic or asymptomatic. After the intervention, 4/20 people in group A are asymptomatic. ...
1answer
35 views

### About comparing standard scores

I have time-series data, from which I would like to detect anomalies. I have Z-scored the time-series, and there is two points which clearly deviate from the baseline. Their Z-scores are 3 and 6, ...
0answers
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### P value significance after FDR correction

I have a question I'm hoping you might be able to answer for me. When running FDR corrections on my data, are there any circumstances under which the adjusted p values can end up becoming more ...
1answer
62 views

### Understanding statistical significance in variance and correlation?

I have little background in statistics. For a dozen items, I have vectors of ratings for these items. I have calculated the variance, and Pearson correlation for these items (using numpy). Now I ...
1answer
164 views

### Two methods of bootstrap significance tests

Using bootstrap I calculate p values of significance tests using two methods: resampling under the null hypothesis and counting the outcomes at least as extreme as the outcome coming from the ...
1answer
66 views

2answers
306 views

### Does an exact test always yield a higher P value then an approximated test?

I ran a simulation on that for mcnemar test, and the answer seemed to be yes. I was wondering if this can always be said to be the case that the exact P value is higher (or not smaller) then the p ...
4answers
536 views

### Alternatives to p-values in R?

In a recent article discussing the demerits of relying on the p-value for statistical inference, called "Matrixx v. Siracusano and Student v. Fisher Statistical significance on trial" (DOI: ...