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1answer
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Mixed-effects model for MZ twin data: avoiding overparametrization

I'm trying to fit a (simple) linear regression using MZ twin data. The reason why mixed-effects are used here is just to correct for correlated responses from the twins. The current model looks like ...
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1answer
18 views

Choice of referent twin in twin difference model

Carlin (2005) points out that mixed effects models specifically for twin data can be simplified by calculating differences between paired clusters. This allows for modeling specifically the within ...
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257 views

How to account for different degrees of familial relatedness in linear mixed model? Is heteroscedasticity a problem?

(Let me preface this by stating that I am somewhat of an R newb and also a LMM newb.) I have a very, very simple research question. I have a continuous outcome variable ("HAPPY"). I have two factors ...
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491 views

Linear mixed-effects modeling with twin study data

Suppose I have some some response variable $y_{ij}$ that was measured from $j$th sibling in $i$th family. In addition, some behavioral data $x_{ij}$ were collected at the same time from each subject. ...