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location Cheltenham, United Kingdom
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seen Apr 25 at 16:35

Jul
26
awarded  Scholar
Jul
26
accepted Observed information matrix is a consistent estimator of the expected information matrix?
Jul
25
answered Observed information matrix is a consistent estimator of the expected information matrix?
Jul
25
suggested suggested edit on Observed information matrix is a consistent estimator of the expected information matrix?
Jun
13
comment How to calculate sample size needed for comparing the “change from baseline” scores between two groups?
You are right in that the two groups are probably unrelated and so we can use a T-test for independent samples. If the first group represents baselines measurments and the second post-baselines measurments on the same people then we can use a dependent sample t-test.
Jan
22
comment Contrasts in mixed model
A correction to the above comment: The $L$ vector should sum to $0$, so if you use $L=(3/4,-1/4,-1/4,-1/4)$ then $L\beta=A-(A+B+C+D)/4$ which is group A versus the average of the other four groups.
Jan
22
comment Contrasts in mixed model
I would try $AvsAvg = L = (1,-1/3,-1/3,-1/3)$, so that if $\beta=(A,B,C,D)'$ then $L\beta=A-(B+C+D)/3$ which is the difference of group A versus the average of the other three groups.
Jan
22
answered Contrasts in mixed model
Jan
21
answered How to calculate sample size needed for comparing the “change from baseline” scores between two groups?
Jan
17
awarded  Teacher
Jan
17
answered Sample size calculation for t-test
Jan
14
comment Observed information matrix is a consistent estimator of the expected information matrix?
@Dapz Please accept my sincerest apologies for not replying to you until now - I made the mistake of assuming nobody would answer. Thank-you for your answer below - I have upvoted it since I can see it is most useful, however I need to spend a little time considering it. Thank-you for your time, and I will reply to your post below soon.
Jan
14
awarded  Supporter
Nov
14
awarded  Editor
Nov
14
revised Observed information matrix is a consistent estimator of the expected information matrix?
added 48 characters in body
Nov
14
awarded  Student
Nov
14
asked Observed information matrix is a consistent estimator of the expected information matrix?