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Oct 18, 2021 at 16:02 comment added Frank Harrell psplines work well so don't switch just for that reason.
Oct 18, 2021 at 14:45 comment added psoares Hi, thank you for your reply! Just to give a bit more background info. delay is the time from symptoms until diagnosis, so I don't expect this variable to have linear behaviour, but I got confused with the output. We used the pspline especially to avoid specifying the location of the knots, but maybe it's best to use a cubic spline and define knots at the percentiles, or maybe at the beginning? Two, three months of delay is quite large theoretically though the median is a bit higher.
Oct 18, 2021 at 13:14 history answered Frank Harrell CC BY-SA 4.0