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Given observations of circular cross sections of a spherical cell ${R_1,R_2.......,R_n}$, with $R_i<R_{i+1}$, find a best estimate of cell(sphere) radius $r$, given that the distances $\sqrt{r^2-R_i^2}$ (say $X$) are uniformly distributed.

I tried to find the distribution of $R_i$ from $X$ as

$F(X)=P(X<=x) = \frac{x}{r}$ so

$P(\sqrt{r^2-X^2}<=t)=P(r^2-X^2<=t^2)=P(X^2>=r^2-t^2)$

$=P(X>=\sqrt{r^2-t^2})=1-P(X<=\sqrt{r^2-t^2})=1-\frac{\sqrt{r^2-t^2}}{r}$

$P(R<=x)= 1-\frac{\sqrt{r^2-x^2}}{r}$

so the density function for $R_i$ is

$\frac{d(P(R<=x))}{dx}=\frac{x}{(r\sqrt{r^2-x^2})}$

so the MLE function is :

$\prod_{i=1}^n\frac{R_i}{r\sqrt{r^2-R_i^2}}$

but this is decreasing with $r$ making $R_1$ the best estimate, which does not seem right as $R_i$ is always less than or equal to $r$, which should make $R_n$ the best estimate, I am not sure where I am going wrong in the process, can someone help me out?

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    $\begingroup$ Maximum likelihood estimators can be biased. For example, the ML estimators for uniform distribution are maximum and minimum of sample, that always lead to a shorter interval. I think your case may be similar, and your math can be right although your estimator is biased. $\endgroup$
    – Pere
    Commented Dec 27, 2016 at 10:22
  • $\begingroup$ Sorry, but can you explain this further, how does bias in a ML estimator work? $\endgroup$ Commented Dec 27, 2016 at 10:33

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Your math seem right - at least, it seems easy to see both by rigorous proof and intuitive reasoning that the maximum likelihood estimator must be the largest observed radius. Furthermore your problem is quite similar to the ML estimate of uniform distribution parameters, which yields the same result.

However, here the ML estimate is always smaller than the real parameter. That's named bias.

Estimators have a couple (useful) properties that look similar but that are actually different: consistency and unbiasedness. ML estimators are guaranteed to be consistent, but they aren't guaranteed to be unbiased.

Consistency means that as the sample gets larger, the estimate gets closer to the actual parameter. It's easy to see that your ML estimator for radius is consistency (the more sections you observe, the more probable that the biggest one get close to the maximum).

Unbiasedness means that for a given sample size expected value of estimate equals the actual value.

It wouldn't be difficult to build an unbiased estimator based on you ML estimator - you only need to multiply it by a factor which will be function of n - but then it will no longer be a ML estimator, although it will remain consistent and therefore it could be more useful than the ML estimator.

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  • $\begingroup$ But the rigorous part is showing that $R_1$ is the most likely estimate, but it should show its $R_n$, I want to understand what should be modified in the above method to arrive at $R_n$ as the best estimate. $\endgroup$ Commented Dec 27, 2016 at 12:03
  • $\begingroup$ @user3932313 Then I see the question I answered wasn't the same you asked. $\endgroup$
    – Pere
    Commented Dec 27, 2016 at 12:30

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