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I am trying to understand the practicalities of Pearl's front-door criteria to estimate causal effects under an unobserved unconfounder. First, to give context to the question we have a graph that looks like this:

Front-door criterion

Where $U$ is unobserved and, hence, no back-door adjustment formula can be used.

We can infer the causal effects on $Y$ of an intervention $do(X=x)$ by using the front-door adjustment formula Pearl (2009 p.81-83):

$$P(y | \textit{do}(X = x)) = \sum_z P(z | x) \sum_{x'} P(y|x', z)P(x').$$

My question is: What is the intuition of conditioning $Y$ on $x'$ ($P(y|x', z)$) if $Y$ is conditionally independent of $X$ given $Z$? Does that mean, in practical terms, that the way to estimate the front-door adjustment is by using the following:

$$P(y | \textit{do}(X = x)) = \sum_z P(z | x) \sum_{x'} P(y|z)P(x').$$

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  • $\begingroup$ Or does it mean that I have to build an alternative estimator using both z and x as predictors? $\endgroup$
    – Sergio
    Commented Feb 5, 2020 at 15:10
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    $\begingroup$ If you haven't read it already, I would recommend Pearl's book The Book of Why, pages 224 to 231. He explains the intuition behind the front-door adjustment formula. $\endgroup$ Commented Feb 11, 2020 at 18:37

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Y is independent of X given Z, but Z isn't independent of X. Which you're manipulating (or, well, simulating the manipulation, anyway).

An intervention on the value of X changes the probabilities of Zs you're going to observe. That's why we need the first part, summing/integrating over the post-intervention distribution $p(z|x)$.

However, both X and Y are influenced by the unobserved variable 'in the wild'. By intervening on X, we eliminate U's influence on X - but not on Y. It's still there, and we still need to account for it.

The $p(x')$ is the pre-intervention probability on values of X, so you cannot use your final equation. The term is actually derived using the independence assumptions to substitute for a $\sum_Up(y|z,u)p(u)$ term. Since U is not easily measurable while X' can be, we're inferring U from pre-intervention X.

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To answer your question straight,

$$P(y | \textit{do}(X = x)) = \sum_z P(z | x) \sum_{x'} P(y|x', z)P(x').$$

can't be rewritten as

$$P(y | \textit{do}(X = x)) = \sum_z P(z | x) \sum_{x'} P(y|z)P(x')$$

because $P(y|x', z) \neq P(y|z)$ in the pre-intervention distribution given the presence of U, the confounder.

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  • $\begingroup$ To explain why you talk about pre-intervention: all probabilities on the right-hand side are pre-intervention, because that is the whole purpose of the front door formula; to compute the probability P(y|do(X=x)) without needing to actually do the intervention. Y is not independent of X given Z in the pre-intervention. $\endgroup$
    – svendvn
    Commented Oct 12 at 21:49

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