Suppose we have $y=X\beta+\varepsilon$, where $\varepsilon \sim (0,\sigma^2V)$, $\sigma^2$ unknown but $V$ known (we can assume a valid $V$ for this model).
Then, by general least square, we can find $Cov(\hat{\beta}_{GLS},\hat{\beta}_{GLS}^T)=\sigma^2(X^TV^{-1}X)^{-1}$ and $Cov(\hat{\beta}_{LS},\hat{\beta}_{LS}^T)=\sigma^2(X^TX)^{-1}X^TVX(X^TX)^{-1})$.
Then, how to show $Cov(\hat{\beta}_{LS},\hat{\beta}_{LS}^T)-Cov(\hat{\beta}_{GLS},\hat{\beta}_{GLS}^T)\succeq0$ (Positive Semi-Definite)? That is, how to prove $\hat{\beta}_{LS}$ is not BLUE in this case?