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I perform a longitudinal experiment and I don t know how to deal with the data dropouts. I use STATISTICA Statsoft but I`m not a professional neither in statistics nor in programming. So the question may seem to be not very smart.

I make a lifespan test on mice during which at stated intervals I measure some parameters since animals` entrance in experiment till their death from age. I guess it would be ok to use factorial ANOVA for repeated measurements if not dying of participants. How can I deal with this issue? If there is a software package for the multiple imputation could you tell me about it? Is it possible to use hierarchical ANOVA (to state animals as a random factor)?

Could you help me? Any advice, protocol or recommendation would be very helpful!

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Have you considered censoring? It's a common technique in survival experiments.

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  • $\begingroup$ Actually not... Do you have any good reference about it? (I`ll search too, but maybe you have it already). $\endgroup$ – Дмитрий Шитиков Apr 6 '16 at 16:14
  • $\begingroup$ The wikipedia link above is okay, it's one of the main search words, so would be survival analysis, which has a russian translation The english translation has a pretty good description, hopefully this one does too. $\endgroup$ – Chris Bonnell Apr 6 '16 at 16:47
  • $\begingroup$ Could you know any short description for ANOVA? Thanks! $\endgroup$ – Дмитрий Шитиков Apr 6 '16 at 18:31

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