I have completed test work following a randomised response surface (multi-factor) experimental design (Central Composite Full) but have found that my levels for two of the factors are not broad enough.

Is there a standardised approach for expanding design of experiments?

I am thinking to: (1) test random central test to validate that I have been able to maintain a consistent standard versus the original experiment tests (using ANOVA / mann-whitney) (2) new tests will simply be those needed to fill the broader Central Composite design (possibly ignoring the ones not needed) (3) test the final model with left over data from the original model to validate


I am hoping that there might be a standard approach to expanding these kinds of experimental design or perhaps using an alternative design so I can minimise the repeats of experiments.

  • $\begingroup$ One standar way of expanding an experiment is to use D-optimal designs. The AlgDesign R package (on CRAN) supports that. You should probably have the new runs in an additional block. $\endgroup$ – kjetil b halvorsen Mar 25 '17 at 17:53

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