I am working on a project which uses a publication that appeared in print in 1998 and reported a completed double blind randomized clinical trial.
Due to the confidential nature of the project I can't give too much detail. The protocol for the clinical trial planned to have three co-primary endpoints. A multiple comparisons procedure was not described in the protocol. In the publication Each of the co-primary endpoints was statistically significant at the 0.05 level.
I'd appreciate thoughts as to whether or not a "multiple comparisons procedure" (MCP) can be "retrospectively" applied to that statistical analysis in this example to a publication completed over a decade in the .
In advance, my view on MCP's is that they should be prospectively planned in order to control Type I error and that there is no justification for retrospective application of an MCP.
thanks in advance