# Non-parametric test for trend

I have non-normal data which are sampled from roughly 4 subjects at 4 dose levels. Is there a nonparametric test for trend I can use in SAS?

• SAS' NPAR1WAY procedure is your best bet. Commonly used nonparametric tests for trend include the Mann-Whitney and the Wilcoxon tests. Here's a link to the SAS support description... support.sas.com/rnd/app/stat/procedures/… – Mike Hunter Mar 10 '17 at 20:35
• Are you trying to perform an ANOVA type analysis where you want a trend alternative (e.g. like $\mu_4\geq \mu_3\geq\mu_2\geq\mu_1$ with at least one strict inequality)? Are you treating the subjects as blocks or as random effects? – Glen_b Mar 11 '17 at 23:59
• I want something approaching testing whether the slope > 0 as the dose gets higher. I would treat the subjects as random effects. – Bosley Mar 13 '17 at 17:15