I have biological data which for example looks like following
chromosome.location methylation.level location_1 100 location_2 0 location_3 0 location_4 0 location_5 100 location_6 50 location_7 100 location_8 0 location_9 100 location_10 0 location_11 100
Methylation.level values are between 0% to 100% in the data file, but biologically methylation level of a chromosomal location in a given time is 0% or 50% or 100%. Both 0% and 100% has big biological meaning. 50% methylation has only little importance.
I have untreated and treated groups.
- Null hypothesis: There is no difference in methylation pattern between two groups.
- Alternate hypothesis: There is difference in methylation pattern between two groups
Which statistical test would be suitable for this sort of distribution?