I'm having an issue with deciding how to correct for multiple comparisons with my structural MRI region of interest analyses. I have two groups, Group A and Group B, and am looking at cortical thickness differences between the two groups.
Before I ran the analyses, I chose 4 regions of interest to look at. I created the cortical thickness maps and then conducted individual ROI analyses for each of the 4 regions, using FSL Randomise.
FSL Randomise does correct for multiple comparisons, and did so for each individual region. However, this doesn't take into account that I ran 4 ROI analyses. So I was wondering how I should account for each ROI analysis.
Thank you for your time!