I am analyzing the paired samples. Patients with drug at time point 0, at time point 12 weeks, time point 24 weeks.
I would like to see the significant differences in the patients over the time points. In other words I would like to see how effective the drug is?
One problem here is I have 10 samples at zero time point, the samples have been given the drug at 12 weeks time point but two samples are missing for some reason. The same for third time point as well. My guess is I wont be able to use paired t test now because of unequal sample sizes.
Which statistical test would be appropriate for this scenario? Any help/suggestions would be much appreciated.
Here is my experimental design.
T0 T12 T24
n=10 8 8