Here is the one-step Q-learning update rule as you gave it:
\begin{equation}Q(s_t, a_t) = Q(s_t, a_t) + \alpha \left[ R_{t+1} + \gamma \max_a Q(s_{t+1}, a) - Q(s_t, a_t) \right]\end{equation}
That update rule actually matches exactly what the "target policy" (greedy policy in this case) is doing; we update the $Q$ value for the state-action pair for which we've just obtained a new observation ($s_t, a_t$, with the new observation being $R_{t+1}$) under the assumption that we follow up with the greedy / target policy immediately afterwards (resulting in $\max_a Q(s_{t+1}, a)$). In this equation, the only action that we may not have taken according to the target policy is the action $a_t$, but that's fine because precisely that same action is the one for which we're updating the $Q$-value.
Now suppose that we try writing a multi-step (or two-step) update rule naively, without importance sampling. That would look as follows:
\begin{equation}Q(s_t, a_t) = Q(s_t, a_t) + \alpha \left[ R_{t+1} + \gamma R_{t+2} + \gamma^2 \max_a Q(s_{t+2}, a) - Q(s_t, a_t) \right]\end{equation}
This update rule assumes that our behaviour policy (typically something like $\epsilon$-greedy) was used to select another action $a_{t+1}$, resulting in an additional reward observation $R_{t+2}$ and state $s_{t+2}$. In this update rule, we suddenly have a problem for off-policy learning, because our update rule uses a reward $R_{t+2}$ that is the result of an action $a_{t+1}$ which our target policy may not have selected, and it's a different action ($a_t$) for which we're actually updating the $Q$-value. Using information from "incorrect" actions is fine if it's only used to update $Q$-values for those same "incorrect" actions, but it's not fine if we're using it to update $Q$-values for a different ("correct") action (an action that would also have been selected by the greedy / target policy).