I'm currently trying to estimate the following equation:

$$y = \text{const} + \beta \frac{x^\gamma}{x^\gamma+\rho^\gamma}$$

So, I have to estimate 3 parameters for every variable plus a constant. A natural choice would be to estimate the equation with Nonlinear LS. However, as usual my estimates depent greatly on the starting values. I also tried to estimate the equation via Maximum Likelihood, as the y-variable follows a Gamma distribution. Nontheless, as the number of independent variables goes up(in my actual model I have 13 x-variables and for each I have to estimate 3 parameters) the ML-algorithm can't converge.

Has anyone an idea, how to handle such a regression? Up until now I tried to estimate the model like this in R.

logLikFun_Gamma_optim1 <- function(param) {
  alpha1 <- param[1]
  beta1 <- param[2]
  rho1 <- param[3]
  gam1 <- param[4]
  rate1 <-  param[5]
  sum(dgamma(y, shape = alpha1+beta1*((x1^gam1)/((x1^gam1)+(rho1^gam1)))
             , rate = rate1, log = TRUE))

  • I have added a formula in mathml code for clarity. I hope that is ok. – Martijn Weterings Oct 10 at 12:45
  • 2
    What is unclear to me in this question is what you mean with "estimate 3 parameters for every datapoint" Does every datapoint get different estimated parameters? How does that work, what kind of estimation are you referring to? – Martijn Weterings Oct 10 at 12:45
  • 2
    I agree with @MartijnWeterings about the 3 parameters for each point ... I think it's 3 parameters overall. Also, your formula has a single x, but you say there are 13. It would also be helpful to know more about the data set (what is the sample size? What are the variables? etc) – Peter Flom Oct 10 at 12:55
  • 1
    If $y$ follows a gamma distribution then what does your equation $y= const + \beta \frac{x^\gamma}{x^\gamma+\rho^\gamma} $ mean? – Martijn Weterings Oct 10 at 13:05
  • What does ML stand for (maximum likelihood, machine learning, ....) – Martijn Weterings Oct 10 at 13:09

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