# Restricting block size in a factorial experiment

I have the following:

It has been decided to run an experiment involving 2 replicates of a $$2^4$$ factorial with factors coded A, B, C & D. However, block size is restricted to 8

I'm not sure what the importance of block size being restricted to 8 is here. For example, what difference would it make if the block size was 6 or 12?

• Is this a randomized multicenter design? – Todd D Jan 14 '19 at 2:30
• I don't understand what that means. If that's the default then yes, otherwise no – baxx Jan 14 '19 at 2:32
• I don't really understand what you are dealing with, maybe some images could help. But intuitively, since your factor has 4 levels (A, B, C, D) then I guess the 8 was chosen such that each block will have a nice integer rep of the factors. – user2974951 Jan 14 '19 at 7:31