I have two possible exposure variables (A and B) for use in a statistical model predicting a binary health outcome. I have fitted models with each variable separately and now know that one variable is a better predictor of my outcome based on a comparison of R-squared and BIC values. However, the ORs for the two variables are quite similar with overlapping confidence intervals. The sample composition and size is the same for each model.

I would like to comment on whether the odds ratios are significantly different from one another. How can I do this?

Best Regards.


1 Answer 1


It looks like you are trying to compare two odds ratios. Try looking at

Statistical test for difference between two odds ratios?

  • $\begingroup$ In this case the 2 ORs are not independent, I'd say. $\endgroup$
    – boscovich
    Oct 7, 2012 at 20:03
  • $\begingroup$ Hi - yes I did see the earlier post, but as a novice I need something with bit more explanation! $\endgroup$
    – N26
    Oct 7, 2012 at 20:51
  • $\begingroup$ As pointed out above, can you assume independence? $\endgroup$
    – Ken Dunn
    Oct 7, 2012 at 20:58
  • $\begingroup$ I'm not sure. How would I evaluate that? Exposure A and Exposure B are correlated to some extent, but rho is about 0.5. $\endgroup$
    – N26
    Oct 8, 2012 at 9:12

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