I'm new to working with matched case-control data. I have a study where case individuals are matched to controls in a 1:3 way. This means that for every case (diseased) I have three matched controls (unrelated individuals). My question is how can perform a t-test concerning a variable for such a cohort between the case and their matched controls. I know about paired t-tests, but how would it work in a case when it isn't a 1:1 match?