I am conducting a project where I comparing a 5 different drugs (anti-psychotics) for a particular treatment group. There are currently no head-to-head trials for me to be able to make direct comparisons.
I have 3-4 trials of each drug comparing them to placebo. On RevMan I have done a subgroup analysis for different outcomes. I do not want to conduct a network meta-analysis. Can I make comparisons on which is the better drug by comparing their pooled odds ratios?
Also when I conduct the subgroup analysis, do I use random-effects or fixed-effect models?
P.s. I am aware of the limitations of just comparing them this way, which I will highlight in my project.