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I have three large RNA-seq datasets, two genes were found to be significant in all three datasets, what is the probability of this happening by chance?

not sure what info i would need so here is everything:

all dataset 1 = 50,240, sig dataset 1 = 187

all dataset 2 = 50,691, sig dataset 2 = 2,942

all dataset 3 = 38,280, sig dataset 3 = 1,428

thank you!

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