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Is there a way to adjust the pooled summary effect size (odds ratio) for confounding factors while performing a meta-analysis in R studio?

I am performing a meta-analysis and I don't want to pool adjusted with unadjusted OR from included studies, so I am wondering if there is a way to adjust the summary OR if I extract raw data.

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  • $\begingroup$ If you have only aggregate data and no access to adjusted OR/HR estimates, than in my opinion you can only try meta-regression. $\endgroup$ – Joe_74 Jun 14 at 8:57
  • $\begingroup$ ok thanks, I will try it out. $\endgroup$ – basma Jun 15 at 13:08

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