# Is it necessary to scale the dependent variable in k-NN regression?

I want run kNN analysis to predict Y (continuous variable). I know that it is necessary to normalize all of the Xs. My question: is it also necessary to normalize Y values?

No, it is not necessary and not needed at all. You just choose the $$k$$ nearest point to your test point, and average their target values to predict the target value of your test point. The distances are calculated using your features, i.e. $$X$$ and are sensitive to scale, not the target variables.