I have the following data:
I have a comparison table as follows:
Can someone help me with identifying which statistical test would help me answer the following question:
Are the chances of getting 350/6500 of the Y genes common with mutant X statistically significant compared to obtaining 20/180 of the Z genes common with mutant X?
I know I cannot use Fisher's exact test for this purpose as "Fisher's test requires the rare condition that both row and column marginal totals are fixed in advance. The resultant 2 × 2 table is described as doubly conditioned."3 What is the test that I can use in this case?