# Should I use repeated measures ANOVA or one-way ANOVA?

I am conducting a study on different image reconstruction algorithms for computed tomography (CT). My aim is to investigate which of the image reconstruction algorithms that have the highest signal-to-noise ratio (SNR). My dataset is 100 patients who underwent a CT brain scan. Each CT scan will be reconstructed with 4 different image reconstruction algorithms. Then I will measure the SNR for each algorithm and patient and compare the different reconstruction algorithms with regard to the SNR. So, we scan the patient's head and then the computer at once provides four different image reconstruction algorithms of the scan (4 different image sets) and then we measure the SNR of each image set and compare it to the other reconstruction algorithms (other image sets). Or, if it makes it easier for you to think. Consider the following corresponding scenario: You take a blood sample (corresponding to "CT scan") from the patient and measure the glucose level with 4 different apparatus (corresponding to the 4 different image reconstruction algorithms). And then you compare the blood glucose level (corresponding to "the SNR") between the four different apparatus. So, my question is if I should use a repeated measures ANOVA or just an ordinary one-way ANOVA.

• It will be easier for people to understand the question/problem if you could describe the dataset. Also, what is your research question ? Commented Jan 8, 2021 at 20:06
• Hello Robert, thank you for your reply. The dataset is the following: 100 patients who underwent a CT brain scan. The CT brain scans will be reconstructed with 4 different image reconstruction algorithms. I will measure the signal-to-noise (SNR) ratio of a ROI placed on a certain brain level at a certain area of the brain. The SNRs will be compared between the different image reconstructions. Should I perform a repeated measures ANOVA since it is the same patients reconstructed with 4 different image reconstruction algorithms? Or should i choose an ordinary one-way ANOVA? Thank you! Commented Jan 8, 2021 at 21:20
• I have updated my question and provided more information about my study as well as a corresponding scenario. Commented Feb 27, 2021 at 11:53