I would like to perform a meta-analysis of time-to-event data for a single group (i.e. there is no comparison group). How do I do so, what are the statistics required?

I understand that for 2-group studies, the effect sizes are hazard ratio and its variance.

I use the meta package in r for my meta-analysis and couldn't find one for time-to-event data. https://bookdown.org/MathiasHarrer/Doing_Meta_Analysis_in_R/

Regards, Hanis

  • $\begingroup$ I would generate a point estimate of effect and relevant variability measure (standard error) for median survival time, or % of patients alive at 12 months (for instance). Then you can use inverse variance weighting. $\endgroup$ – Joe_74 5 hours ago

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