I have some background in stats and math but it has been a bit, and I'm not sure if there is some nuance to this question.
We have 15 chest x-rays for pre and post treatment effect.
We have three radiologists who make measurements on each of these 15 chest x-rays pre and post treatment.
I understand that if there were only one person taking measurements, there would be 15 pre and 15 post measurements, and a paired T-test would absolutely be the right test.
But, since we have three radiologists taking measurements of the same 15 chest x-rays pre and post treatment, is a paired T-test still appropriate? And would it just be a T-test on 45 pre and 45 post treatment X-ray measurements? Or is this sort of a repeated measures or multiple paired T-test sort of thing?
Please let me know if I am being unclear. I would appreciate any information or opinions.