I'm reading about Design of Experiments via various textbooks (e.g. Montgomery's), and powerful global optimization methods (such as Ant Colony Optimization) are not used. They rely only on a basic sampling scheme in the search space; full factorial or otherwise, and then fit a linear model (perhaps with quadratic and interaction terms) of the experimental factors onto the response variable. Then they use that model to estimate optimal values for the inputs in order to maximize that response variable.
What is the purpose of limiting methods like this? Just deploying global search algorithms would result in a better optimization outcome.
EDIT:
I understand that optimization isn't the only (or main) purpose of DoE, but it's often part of the purpose. See for example chapter 11 of Montgomery's textbook titled Design and Analysis of Experiments, where optimization is the focus. I wanted to know why powerful search tools are not considered when optimization is a big part of the goal.