I have two groups of samples with a proportion of mutations in each sample being a particular type (the proportions are represented as a fraction of 1). How to I check if that type of mutation is significantly likelier to happen in one group over the other?
Partially answered in comments:
You could use a χ2 test for proportions. – user25658 If you want to be able to consider both one- and two- tailed tests, what about a two-sample proportions test? – Glen_b