These concepts have always confused me. In terms of DOE, I think the problem arises when the design is "unbalanced". So,
- what are their differences?
- Why do you choose one over the other/reasons?
In one-way ANOVA, does using (can you?) LS means makes sense or LS means is only for two-way ANOVA and onwards?
For ex: In a simple study, say, I am comparing if there is a diff. in height between M and F. I have an unbalanced design, say, I have more M than F (I selected equal sample, but some ppl died and this is what I have to use) Does having LS means means anything in this scenario? Or LS means= unweighted in this case?
Can anyone please clarify in a simple and intuitive manner?