# Multiple imputation

I am running multiple imputation for a set of variables including clinical data. I am wondering if I can use (or should use) outcome variable (follow-up is 99%) to predict missing clinical data. There is about 12 % of non complete cases due to mostly one variable. I intend to use Amelia package (R)?

Some extra information included from comment:


Providing that there are same baseline variables missing do you exclude lost to follow-up patients and then run multiple imputation method or do include patients lost to follow-up and than run multiple imputation method. What is the correct approach?

I would be most grateful for answer.