In order to build prognostic model for predicting breast cancer risk, the sample of 321 women has been formed. Each woman answered the questionnaire, and the answers were used as predictors. The outcome was whether the women has breast cancer or not. We have collected 132 patients with breast cancer, and also 189 women without breast cancer answered the same questionnaire. So the incidence of breast cancer in the sample is about 0.41. But in population the incidence is about 0.0005 per year. Consequently, not only breast cancer, but each harmful factor has greater incidence in the sample than that in population. Now, I've obtained OR for smoking about 35.
exp(intercept)of the model, then it is also close to 35. And if it is incidence among nonsmokers from sample, then $RR=2.7$. Is any of these options right?