I was helping a friend with some problems for a clinical trials administrations course they are taking, most of it was simple statistics the last question was a little more tricky. We got the answer from google but it made me think a bit the quesiton was to do with patients dropping out of a trial with time without achieveing the requisite follow-up period. I was wondering about a simper case.
Consider a simple trial where I compare two different interventions. Patients are assigned to one of two interventions randomly, 100 into each arm. My end point is a single continuous variable. If, for whatever reason, only 94 patients in one arm and 97 in the other are suitable for analysis does this affect my analysis beyond the obvious increase in random uncertainty?