Since you're looking for a statistical test, I'm assuming what you want to know is if there is a significant difference between the case group and the control group, and if there is a significant difference between those who use > 1 narcotics and those who use <= 1 narcotics. Am I right?
In that case, you want to use a 2-way ANOVA because it's easy and simple. You can do this test on software or some online site will probably do it for you for free. Here is a link to the Wiki for the test. Here's a link to a site that will do the test for you.
What you have to keep in mind though, is that ANOVA assumes a normal distribution. Plus, you can't perform 2-way ANOVA unless you have at least more than 1 replicate in one of your tests. The power of the test also decreases if you don't have the same number of replicates in all cases.
The way to evaluate the test is, if the p-value is less than 0.05, you say that there is a difference between the groups.
For your data, you can't perform 2-way ANOVA just yet because you lack a replicate (a repetition). I recommend you get another replicate first. Otherwise, you will have to do two one-way ANOVAs since that allows single replicate analysis.