Questions tagged [baseline]

A base measurement for comparison. Usually a measurement prior to treatment, of a control condition, or of the assumed population.

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Adjusting for baseline when time is a covariate, what is the interpretation of $y(t=0)$?

When one aims to estimate the treatment effect over time, it is recommended to include the baseline value as a covariate. Assume continuous outcome $y$, continuous time $t$, categorical treatment $x \...
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How is it possible, that statisticians have OPPOSITE view on the analysis of change from baseline adjusted for baseline?

I always thought, that mathematics, thus statistics, are both strict sciences. So, two mathematicians cannot speak about the same topic and have contrary views on it. In the pharmaceutical industry, ...
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Why is the baseline x time interaction included in clinical trials models (MMRM)?

I noticed, that many, many times, when the longitudinal studies are analysed for efficacy, the following components are taken as fixed effects: time treatment time : treatment (interaction) baseline ...
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How to adjust for the baseline difference between groups for a histogram

I have data from an experiment that tested responses to stimuli in females and males. I measured baseline for both groups prior to presenting the stimuli. The baseline for males is higher than for ...
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How simple should a Baseline model be?

I was making baseline model and was wondering how much time I should spend on it. I've found a lot of article about the purpose of a baseline model, for instance; A baseline takes only 10% of the ...
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Why the baseline algorithm irls from the R baseline::baseline() function can generate negative values given a positive signal in input?

I am running the baseline function on the following signal in order to find peaks. Why is the computed baseline negative in some regions?
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How to measure a pre-post change?

I would be very grateful for any advice on how to analyze the data of a small study I have conducted. The study has only one group of participants and their performance in a test was measured for 5 ...
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Values of reference categories for main and interaction effects using lm() in R [duplicate]

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Is it a problem if my model does not perform as well as the stupid model?

Usually what I see is that the baseline accuracy and the base model have different accuracies so then the goal is to clean the data and do some feature engineering etc to build a model that performs ...
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Baseline adjustment when both pre- and post values are subject to left-censoring

Assume $X$ is a binary treatment variable, $Y$ is a continuous variable measured pre- and post-treatment $(Y_{pre}$, $Y_{post})$, and $Z$ represents the remaining covariates. Both $Y_{pre}$ and $Y_{...
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How to check baseline covariate balance after variable ratio matching?

In my case, each active subject is matched to a variable number of control subject. The way I can think of is to first average across the control subjects for the same active subject to make a 1: 1 ...
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how to calculate median follow-up time?

I have a hospital based dataset which conatins information on patient details. Right from their visit, drugs, diagnosis, lab tests, and death info etc. So, now I would like to compute their follow up ...
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Analyzing impact of baseline value on change score using lmm

I'm using a big clinical data set with a the evolution of a continuous lab value over time being the dependent variable and I am interested in the impact of the baseline of this value on this ...
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What is the baseline model in structural equation modeling analysis, what it may look like?

I am reading (also learning) a paper using structural equation modeling (SEM) as their analysis method. Their analysis was constructed by using a correlation matrix and asymptotic variances. They ...
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First Time Point in an LS Mean Plot with Baseline Control

Hoping you can help me understanding a request that my supervisor would like me to do in an LS Mean plot. My model is the following in lme4: DV ~ Group + Time + Group x Time + BaselineScore + ...
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For retrospective observational studies how to determine the baseline of control subjects

I understand that for the active treatment group you can consider the start of treatment as baseline. How about the control group? It is difficulty to do matching without resolving this problem.
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Significant difference between randomized groups at baseline?

A collegaue and I are conducting a pilot study in a school, the aim of which is to assess whether an "alternative" educational tool is more or less effective than traditional teaching ...
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Baseline controls for clinical trials in mixed models through random effects?

I'm analyzing multisite clinical trial data with mixed models. I have (a) a continuous DV, (b) a grouping variable (treatment vs control), (c) baseline scores for the DV, (d) a time variable (baseline,...
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How to handle large baseline difference in a randomized trial

I have results of a randomized trial where 200 participants were randomly allocated to 2 intervention groups and outcome evaluated 1 month later. I believe baseline differences between 2 groups are ...
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Which variable to take as reference category? [duplicate]

I'm doing a research about the relationship between investment risk tolerance and demographic factors such as age, generation, survey year, and control variables (including education levels,...) and I ...
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Why we cannot take baseline as predictor for change in this case

It is generally recommended that baseline should not be kept as predictor if change is outcome variable. Explanations for this have taken both baseline and final values as random (e.g. see here). ...
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Keeping baseline as predictor with change score as outcome in this peculiar scenario

It is generally recommended that baseline should not be kept as predictor if change score ...
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Is there a mathematical proof for change being correlated with baseline value

It is shown in answer here and at other places that difference of 2 random variables will be correlated with baseline. Hence baseline should not be a predictor for change in regression equations. It ...
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Using baseline categorical response as a predictor

I have a longitudinal data where the categorical response is collected at two-time points. I was wondering if it's possible to adjust my categorical response at baseline as a predictor and run a ...
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What are the advantages and disadvantages of including a baseline measurement variable in longitudinal data analysis?

What are the advantages and disadvantages of considering a baseline measurement variable in longitudinal data analysis? (A baseline variable could be the number of seizures each patient had per ...
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Base Error Rate

I am working for my final exam and I saw this sample question: Given this dataset, Assume we have the following gender detection problem, given the observed hair length and height (both discrete ...
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