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Assess sensitivity of a binary screening result across other continuous covariate(s)

I want to assess the sensitivity of a diagnostic screening test, which is a binary test (screen +ve and screen -ve). There is no continuous measure from this test - it is literally yes or no. My ...
Dilsher Singh Dhillon's user avatar
1 vote
0 answers
1k views

Calculating sensitivity and specificity from survival data

I have a diagnostic test performed on 100 participants at baseline. I then follow up these participants for variable periods of time and have data regarding survival. I have used a Cox regression ...
RobMcC's user avatar
  • 253
4 votes
2 answers
707 views

What happens with sensitivity and specificity after a second test?

What happens with sens/spec and PPV/NPV if one performs a test twice (or three times etc.)? I will give an example from my own clinical practice. At many hospitals, we have a problem with ...
Johan_A_M's user avatar
2 votes
2 answers
959 views

Relationship between ROC curve and statistical significance in comparison of two groups

My question is about any possible relationship between the significance of a comparison test (Mann-Whitney U) and the ROC curve. If the comparison test is strongly significant, should we expect a ...
Panos's user avatar
  • 21