Questions tagged [incidence-rate-ratio]

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Use of probabilistic sensitivity analysis in determining incidence over time

I'm plotting incidence (y, per 10,000 population) over time (x, years) using results from a simulation model. And seeing when the incidence reaches below a certain incidence target (1/10,000). It was ...
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1answer
13 views

Determining the statistical significance of change in incidence rates

What is the approach to use to determine the statistical significance of change in incidence rate over years? Below is at table showing such kind of data of incidence rate per 1000. ...
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Comparing Surveillance Positive Cases' Demographics

I am examining surveillance data of two diseases. I have frequencies of demographics such as age, sex, race/ethnicity and would like to compare the rates of these demographics between the two diseases....
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13 views

Converting from incidence rates to raw counts using separate datasets?

I wish to estimate the proportion of all breast cancer patients who are white, black, etc. There are many statistics of incidence rates within each race group, e.g. breast cancer incidence within ...
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1answer
16 views

Is there a way to compare incidences of 2 diseases in the same cohort?

I would like to compare incidences of 2 diseases in the same cohort for the past 10 years. Eg. I want to see whether there's an association between incidence of heart disease and incidence of ...
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1answer
114 views
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Creating confidence intervals for rates per 100,000 with very small numerators? [duplicate]

I am conducting a study comparing rates per 100,000 of new HIV diagnoses over time in certain regions. I intend to calculate 95% confidence intervals for each rate. However, some of my numerators (HIV ...
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1answer
83 views

Meta-analysis with random effects on prevalence data with > 2 possible outcomes: is it necessary that the weighted prevalences all add up to 100?

I am running a meta analysis on prevalence data. Participants can belong to one of four groups. Each study produces the percentage of participants that belong to each group (e.g., Group A: 50%; Group ...
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25 views

Which statistical analysis model to use to calculate the relationship between diabetes incidence and endothelial function?

I have longitudinal data with 2 follow ups at year 1 and 3. At baseline we have measure of endothelial function and we want to calculate the relation ship between endothelial function and diabetes ...
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1answer
68 views

What is the difference between 1-year partial prevalence and annual incidence?

In cancer research, like in this article, partial prevalence is sometimes used to assess the epidemiological state of a disease in a population. The document I'm trying to understand (link, in french)...
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156 views

Interpreting incidence rate ratios (IRR) in panel data

I am running a negative binomial panel regression (xtnbreg) that includes a pre/post estimator for an intervention (with controls) and am trying to understand how the incidence rate ratio should be ...
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1answer
64 views

How to model counts of a categorical variable?

I'm interested in assessing the impact of various covariates (age, sex, Charlson comorbidity score, etc.) on the incidence rate of a pulmonary event. However, the event is not binary. Each patient ...
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1answer
33 views

comparing incidence rate

I have a data set of individual level data for the outcome in question. I also have aggregated data (at a national level) from which I'm obtaining the denominator. Using this information, I've ...
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11 views

Test for yield and disease incidence in block design

I need to analyse a set of data coming from an agricultural experiment, with the intention of assessing the incidence of a certain disease in potatoes under three different treatments (plus blank). I'...
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1answer
65 views

Calculate incidence rate per person or in total

For my study I am doubting about the following: First I want to present the incidence rate for patients who received an CT-scan. I thought I would just count all the CT-scans that took place and ...
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1answer
1k views

what is x per 100 person years mean?

In medical papers, it is very common to calculate incidence rate and mention it's unit as per 100 person years. What does this means? I know that incidence rate is the amount of people got the event ...
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34 views

Confidence intervals for Ratios of Correlated (nested) Age-Adjusted Rates

I am interested in calculating the incidence of disease in an ethnic subpopulation (denoted $X$) and comparing this with the incidence in the entire population ($\Omega$) (where $X$ is a true subset ...
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22 views

Modeling hip fracture incidence (hospital-based cohort design)

Hoping someone can help me out with a question I have on an analysis looking at prosthetic hip fracture incidence following hip replacement surgery (exposure=type of implant, with reference being the ...
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2answers
206 views

Validity of non independent observations in Poisson regression when modelling incidence rates

I have a question regarding fitting a poisson model to non-independent observations when assessing the incidence of an outcome. I am interested in the incidence of some outcome, O, over time. I have ...
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3answers
253 views

Calculate probability of disease appearance

I am a doctor so please be kind with me and my basic understanding of statistics. I have a dataset consisting of patients and their visits and I have labelled the presence of a specific kind of mole ...
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1answer
68 views

Visualize the rate of reported cases of disease with respect to the population

I have to do some visualizations about vaccines. I downloaded data on reported cases of vaccine-preventable diseases (for example, measles, tetanus, etc.) here. These data are absolute values. I ...
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435 views

Interpreting Poisson regression model [duplicate]

I am having a mighty difficult time interpreting the following results given to me based on a generalized linear model with a Poisson distribution: Data: data represents the number of visitors to a ...
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34 views

Standardized Infection Rate from predicted probabilities. Which method?

I need to calculate the Standardized Infection Rate (SIR), that is the ratio between actual cases of infection and predicted cases based on a predictive model. According to CDC https://www.cdc.gov/...
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1answer
359 views

Compare incidence rate

During the follow-up time, event A will happen multiple times, and there are 3 types of A, I call it A1, A2 and A3. I wonder if there is a statistical method that I can calculate the incidence rates ...
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423 views

Interpreting incidence rate ratios in poisson without exposure variable [duplicate]

I have a dataset made up of observations of procedural cases, with a count outcome (variable X carries the number of times a specific finding was detected in one procedure/case). My denominator is the ...
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252 views

Calculation of person years in a cohort study for survival analyses

I am analysing data from a cohort study using primary care data (but I linked them up to secondary care data only for the outcome). Specifically, I am looking at the adoption of a specific care ...
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1answer
416 views

How to calculate relative risk if the reference group has an incidence of 0?

this appears to be a quite difficult question. As we know, if 20% of the smokers developed lung cancer and 10% of the non-smokers developed lung cancer, then we say that cigarette smoking is ...
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1answer
372 views

Adjusting variable for covariate to calculate rates or metric

In this report by Dartmouth Institute, rates of utilisation (per patient) were reported by year and regions. The input measure of utilisation were said to have been adjusted for differences in age, ...
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2answers
937 views

Incident rate ratios with log-transformed variables in Poisson regression

I'm in a bit of a mess with interpreting the output of a Poisson regression model with log-transformed predictors. The predictors are counts, and the log transforms them for the linear part of model. ...
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1answer
68 views

Can odds ratio be in different direction to rate ratio?

My question is whether it is plausible to have "Rate Ratio" showing an increased risk while "Odds Ratio" (based on the same data) showing decreased risk? I have an example in this article: http://...
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48 views

How to Assess Significance of the Difference in Incidence Rate Ratios?

Imagine we estimate two sequential negative binomial regressions. In the first one, we use say 3 predictors (x1, x2,x3), and in the second, we use the same 3 plus an additional variable (x4). We are ...
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2answers
65 views

What type of statistical test should be used to compare successes of two treatments?

Say I have two treatments, "hot" and "cold". I care about a certain outcome, say "success". I have data on the number of successes out of, say 100 trials in the "hot" treatment. Similarly, I have data ...
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133 views

Interpreting categorical x categorical interaction in a poisson regression [duplicate]

I have run a poisson regression with two categorical predictors (treatment and disease severity) and their interaction, controlling for a number of relevant covariates. Treatment has two levels (...
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296 views

Are these negative binomial regression results reasonable?

I did a negative binomial regression on a data set with 4 covariables. The count outcome has values up to 600. I did a mixture model with 2 components, also called a latent class model. However, I am ...
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2answers
4k views

How to calculate 95% CI for cumulative incidence rate using R?

for example, 30 events during 10000 person-years, the cumulative incidence rate is 3 per 1000 person-years, how to calculate its 95% CI?
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212 views

Modeling incidence rates in family-based cohort: Poisson vs Cox

I have a cohort made of family trios and affected sib pairs (probands have rheumatoid arthritis - RA). I would like to calculate some incidence densities (for example apparitions of RA, of disease 1, ...
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1answer
58 views

Relationship between survival time and incidence rate

I am working on an operations issue. We process patients in care and pay close attention to their discharge rate, which is more or less calculated as an incidence rate (discharges per 100 patients). ...
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1k views

Can you calculate a standard error from confidence intervals?

Specifically, can I calculate a standard error from an incidence rate with known confidence intervals but no population size data?
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1answer
2k views

How can I calculate a confidence interval for a rate ratio, if I only have the rates?

I want to calculate the 95% CI for an incidence rate ratio (IRR), but I only have incidence rates per 10,000. (I do not have counts for the 2x2 table.) Specifically, the incident rates were ...
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1answer
662 views

Can I compute the p-value for a list of incidence rates?

Coming back to statistics after a long time, so please forgive any ignorance. I'm curious how I might be able to argue for statistical significance of a test. Specifically, I'm after a ...
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1answer
755 views

How to compare two incidence ratios statistically- the rate parameter test

I want to compare two standardized incidence ratios (SIR) obtained in stratified analyses. I read in Mocci et al (2013) that they used the rate parameter test and cited the book Statistical models in ...
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1answer
901 views

Calculating OR and IRR for a zero-inflated negative binomial model from estimates

I used the PSCL package to run a zero-inflated negative binomial model on some count data I have. This package gives the following output: for the zero part of the model: ...
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776 views

Calculating p-value from chi-square when comparing two incidence rates

I am trying to follow this guide to calculate the p-value from an incidence rate between two samples. The raw data is patients' use of an action plan before and after education. Before education 7 ...
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2answers
333 views

Survival rate trends in case-control studies

I submitted an article which was rejected due to the improper way of performing the survival analysis. The referee left no other details or explanations other than: "survival analysis on time trends ...
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50 views

Aggregating rates of events in a population

For every 100,000 people, 4 people succumb to event $X$, a different 10 to $Y$, and 2 others to $Z$. I would like to know the number of people that succumb to any of $X$, $Y$ or $Z$ per 100,000. Is it ...
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1answer
375 views

Since incidence rate ratios are always positive, how does one determine the sign of the effect?

I want the results from a Poisson regression to be comparable to previous OLS and Tobit regressions. To do this, I am utilizing the irr (incidence rate ratio) option in Stata. However, since all the ...
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1answer
3k views

Interpreting negative binomial regression with log transformed independent variables

My independent variables were highly skewed, so to normalise the distribution they were log transformed. Also since there were zeros in the data, I've added + 1 to transform the variables. This is ...
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0answers
437 views

Estimating mortality rates with direct age-standardization

I'm attempting to calculate the mortality rates of AMI (acute myocardial infarction) in patients (cases) with high bloodpressure, between the years 2001 to 2008. For every case I have 2 matched ...
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667 views

Interpretation of log transformed predictor in negative binomial regression

I mainly want to make sure that I'm making the correct interpretation here. I built a negative binomial regression model predicting a count variable. There was evidence of overdispersion or I would ...
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1answer
6k views

Calculate incidence rates using poisson model: relation to hazard ratio from Cox PH model

I want to calculate incidence rates to present along hazard ratio's in order to present both relative and absolute measures of risk. I saw in other studies that such incidence rates can be calculated ...