Questions tagged [meta-analysis]

Methods focused on contrasting and combining results from different studies, in the hope of increasing precision and external validity.

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how to combine effect size of wilcox test

I am doing Wilcoxon signed rank test on paired samples and it only reports effect size r and p-value. Since I am doing a meta-analysis and have calculated many effect sizes, I want to combine the ...
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How to pool regression coefficients

I have a question in the area of meta research. I have a dataset that consists of regression data of several economics papers. More explicitly, I have the values of the regression coefficients, the ...
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31 views

How do I interpret results of a mixed effect linear regression with 7 independent variables accounting for variability of one dependent variable?

I have 7 moderators while fitting the mixed effect model using the metafor package, my results show many interactions and I am a bit confused on how to present ...
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1answer
173 views

How do I translate logistic regression output into logged OR (and SE) for meta-analysis?

I'm attempting to conduct a meta-analysis using (logged) odds ratios, I'm using the Generic Inverse variance method (Review Manager) as some of my studies only report odds ratios and CIs (not raw data)...
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Presenting results of a meta-analysis with multiple moderators?

I wish to present the results of my meta-analysis using the best practices possible. I do not find, however, examples in articles similar to what my output is. Here's a simplification of my model and ...
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1answer
794 views

meta-analysis of linear regression coefficients

I have the summary results of a linear regression model with 26 covariates which has been fitted to two independent samples (with different sizes). Now I am planning to use the linear regression beta ...
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selection of meta-analysis model

I have a dataset which includes different publications, and different studies within each publication, different variables were also collected (i.e. var1, var2, and var3) and one effect size y. var1: ...
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Meta-analysis model

I have a dataset which includes different publications, and different studies within each publication, running fixed and random effect model for the same data for all studies, both models reported the ...
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Two tests for the same question

We have two series of scores (continuous variables) obtained for two groups of students formed randomly from a population for which we ask ourselves whether an intervention (a teaching method for ...
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1answer
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In a meta-analysis, can you back calculate estimated group proportions from risk difference?

In a meta-analysis of the risk difference, does it make sense to apply the weights & back calculate the expected proportions in each group? For example, if you had the following: ...
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1answer
21 views

Calculating Effect Size from Wilcoxon W value (how to get the z value)

Im carrying out a meta-analysis where I have had to carry out my own wilcoxon test on the data. I am now calculating the independant effect sizes for each study to manually input to my excel ...
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237 views

Are there good alternatives to Cochran's Q test for heterogeneity in meta-analysis?

We used the Q test to determine heterogeneity with p-values <0.10. A highly recognised statistician commented that the Q test has low power and that it should not be used to determine presence of ...
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Multi level meta-analysis model

I'm working on meta-analysis in the agricultural sciences. I have four groups a, b, c, d which are nested within each study. One paper can have multiple studies and each study may have data from ...
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1answer
158 views

Permanova outputs with or without random factor

My question is similar to this previous post but remained unanswered. I am having trouble understanding the output of an adonis models with and without the argument “strata” in the formula. I want to ...
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What are key differences between homoscedasticity of effect-sizes and homogeneity of variance?

The terms - Homoscedasticity and homogeneity of effect-sizes are frequently used with respect to regression analysis/ Anova.These assumptions create lot of confusion at least in my mind. I am not ...
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Meta analysis Model

I'm working on meta-analysis in the agricultural sciences. I am looking for feedback on the rma.mv structure below for a multi-level model in metafor. The data are structured such that: each group (4 ...
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1answer
262 views

Coding nested factors for 3-level in rma.mv function of metafor package

I'm working collaboratively on an arm-based, network meta-analysis in the agricultural sciences. After carefully reviewing the Konstantopoulos walkthrough and Viechtbauer's slides to develop the code, ...
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24 views

how to estimate means and SD from clustered means in a study

for conduction of a meta-analysis I am collecting data from various studies. Unfortunately, not every author provides means for all groups, instead, means are clustered. Say, I have independent ...
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1answer
25 views

Why 95% confidence interval is different for some studies in meta-analysis in “meta” package in r?

I am trying to do a meta-analysis using hazard ratio, lower and upper 95% confidence interval in meta package in R but for example Blazek study, obtained upper and lower 95%CI ([0.6023; 1.5944]) were ...
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Meta analysis of Multiple regression

I have 10 predictor variables and one outcome variable. However, I used three scales to measure the outcome variable. I conducted three separate regression analysis, with one of the three different ...
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1answer
348 views

What does the Hedges g mean in this meta-analysis?

https://www.medicaljournals.se/jrm/content/html/10.2340/16501977-2210 I am looking at the outcome scores of the WOMAC for the three studies included in the metaanalysis linked above, but I am having ...
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35 views

Can linear and logistic regression coefficients be combined using an inverse variance weighted average?

Suppose I have coefficients from several studies, some are linear regressions and some are logistic regressions. They measure the same construct, but because of the nature of the experiments (i.e., ...
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1answer
51 views

How to correctly interpret rma.uni output?

I am posting this question here after being advised to do so on StackOverflow. I am trying to use the rma.uni function from the metafor package to estimate the impact of fishing gears on my abundance ...
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estimating variance estimates in regression study using CMA

I am doing a random effect meta-analysis using CMA. I have a study that uses regression to analyze the data. The article provides standardized regression weights, f squared (regression equivalent of d)...
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2answers
542 views

Estimate ROC curve using binormal distribuiton

I am conducting a meta-analysis on diagnostic studies but for each study I have only mean and standard deviation reported. How can I estimate the ROC curve using the binormal assumption in R ? Tks,
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1answer
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Stratified logistic regression with log link

I noticed the other day that I can mimic a stratified logistic regression using a meta-analytic approach at least when there is only one stratification variable with two different values. This is the ...
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1answer
883 views

Effect size calculation for Kruskal-Wallis mean rank test

I have a published paper in which I'm attempting to calculate the effect sizes for various outcomes. For a pre-post scale, the authors report the sample size, mean rank, and p-value for an outcome (...
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adjustment for cluster RCTs in meta analysis

Can anyone tell me how to account for clustering while conducting a meta-analysis? I read the Cochrane handbook but it still seems unclear to me. I included several cluster RCTs in my MA, I followed ...
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Which binomial confidence interval is correct?

Background: I am working with a data set that requires a transformation. It's prevalence data so I have proportions to deal with, and as the proportions are quite low, I'm using the Freeman-Tukey ...
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standardized mean difference including between and within subject designs

I am in the process of drafting a meta-analysis for a research project. The document makes use of a forest plot (random-effects model) that depicts the standardized mean difference of each study along ...
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Correction for sample overlap in a meta-analysis of prevalence (metafor package)

I want to conduct a meta-analysis of around 30 studies (from a systematic review). Some background of the studies: The quantity of interest is the prevalence of RSV infection. Different studies ...
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1answer
28 views

Unusual problem with metafor:rma output

I have a rather unusual problem with the output of my metaregression using metafor:rma. When I attempt to calculate the confidence intervals for the tau, i, and H values, all of the estimates are ...
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1answer
151 views

Meta-analysis of standard deviations

Does anybody know whether it's possible to conduct a meta-analysis, outcome of interest being difference in standard deviations between two medical interventions, instead of the difference in mean? ...
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Combining two datasets for Random Forest binary classification

I was tasked to perform a brief meta-analysis between three datasets, all with identical features, that studied different sources of neurodegeneration. As a meta-analysis these datasets were drawn ...
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Vastly different I-squared scores between metagen and metareg outputs

I've calculated a meta-analysis using the package Meta in r. The results of my analysis indicated an I-squared value of 82%: ...
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1answer
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Is there a way to create the forestplot in R metafor, which presents only subgroup summaries (no individual studies)?

Is there a way to create the forestplot in R metafor forest(), which presents only subgroup summaries (no individual studies)? ...
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1answer
20 views

How do I standardize regression coefficients for use in a meta-regression?

I am trying to run a meta-regression, in R, using regression coefficients from multiple studies. The models from these studies tend to differ (Logistic/OLS/Weighted Least squares/2SLS). Is there a ...
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9 views

One sample Cohen's h variance to conduct a meta-analysis

I am performing a meta-analysis where my effects are mainly one-sample test against the chance level. Let's say that we have n subjects that perform several trials with a binary response (correct, ...
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1answer
25 views

Meta analysis: rma vs. metaprop (funnel plot-related)

I have a problem, which is beyond my ability to solve. So, I am trying to use two different meta analysis functions (in R): rma and metaprop. In case of rma, ...
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39 views

Can correlations between all variables be extracted from PCA/RDA biplots?

I am performing a systematic review of the literature for my dissertation, and I need to extract the relationship between two variables from the results of multivariate analyses, particularly ...
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1answer
26 views

Meta analysis: Covariate adjustment?

I am doing meta analysis using "rma" (function) in the "metafor" package (in R). And this is my first time to do meta analysis. The estimate is a proportion (# of patients with ...
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23 views

Metafor package: choice of moderator for bias correction

I am doing a 3-level meta-analysis using rma.mv() function. I found a thread about bias diagnostics with an advice to use "regression test for funnel plot ...
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1answer
30 views

Meta-analysis in R: how to calculate standard error for study with multiple outcomes?

for my PhD, I am working on a meta-analysis. The studies we have identified have means/SDs and % to compare conditions. Several of these studies also have multiple outcomes that we want to pool. For ...
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2answers
232 views

Is it possible to meta-analyze means on different scales?

I have study-level means/SDs reflecting depression symptom severity from multiple single-group studies. I do not have access to participant-level data. The studies all use different measures, and I ...
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1answer
27 views

Calculating variance of one-sample cohen's d effect size

I'm trying to perform a meta-analysis where my effects are mainly one-sample t-test against chance level. I've easily found the one-sample cohen's d formula but I'm not able to find the variance ...
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1answer
551 views

Meta-analysis: How can I compute the sampling variance of Fisher's z-transformed correlation coefficients for within-subject designs?

Rosenthal and colleagues (Rosenthal, Rosnow & Rubin, 2000) suggest that it is possible to compute r (correlation coefficient) as an effect size from repeated measures designs (e.g., by converting ...
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1answer
306 views

Testing multiple comparisons of paired proportions

I want to know if a proportion increased significantly after an event, and then find out if that holds true over multiple events. I'm using a paired t-test to measure this with continuous data (e.g. ...
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0answers
17 views

Creating Z-Scores for Meta-Analysis

I will be conducting a meta-analysis that compares post-treatment changes in depression between the control and intervention groups. I have the Mean, SD, and N for depression at both time-points. ...
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1answer
134 views

Using p-values reported as inequalities such as $p<0.05$ in meta-analysis; can I convert them to $0.05$?

I am currently undertaking a meta-analysis of the expression profile of specific biomarkers in a specific disease. During the extraction process, I extracted the name of the biomarkers and their ...
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How to do meta-analysis of diagnostic tests with only sensitivity and specificity?

I am a junior physician, and I've run into some problems with the meta-analysis of diagnostic tests and I was hoping to get some input. Some background: Aside from my undergraduate statistics courses ...

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