# Questions tagged [meta-analysis]

Methods focused on contrasting and combining results from different studies, in the hope of increasing precision and external validity.

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32 views

### Calculating SMD from posttest only - is this possible?

I am performing a meta-analysis (with 'metafor' R-project) as described by Becker (1988), and I compute the standardized mean change for a treatment and control group. I compute a (standardized) ...
65 views

### Calculation of I-squared in meta-analysis of diagnostic accuracy

I would like to calculate heterogeneity statistics (Cochran's Q, I-squared) for a meta-analysis of diagnostic accuracy. I successfully used the 'mada' package in R to calculate these statistics, but ...
111 views

### How to compare fixed effects of linear mixed models

I have two linear mixed models that I ran with the lmer function from the lme4 package. The models are identical except that I ...
38 views

### Statistical test to compare two proportions

I am performing a meta-analysis comparing proportions of patients diagnosed with a disease based on 2 different diagnostic criteria. I have collected and pooled proportions rates (patients with a ...
127 views

### Simple Bayesian meta-analysis in R [closed]

Is there a simple way to conduct a Bayesian meta-analysis in R in order to support equivalence between the effects of two study types? E.g., Bayes factors would be perfect. So, for example I have ...
34 views

### Meta Regression- Average AGe

I want to conduct a meta-regression, using the variable. The studies in my meta-analysis include studies, that compore two indipendent groups. My question: to calculate average age of a study - is it ...
49 views

### Meta-Analysis - Calculating SE from given ES

I have the following problem. I am trying to conduct a meta-analysis and I have an effect size estimation of some unpublished studies. Unfortunately, I don't have the Standard Errors for the mentioned ...
51 views

### What transformation can I use to enable a relatively unbiased meta-analysis of $\alpha$ reliability?

I want to meta-analyse reliability estimates. For simplicity, assume the reliability estimate in question is Cronbach's $\alpha$ (aka Guttman's $\lambda$-3). Various packages exist to do meta-analyses ...
16 views

### Pseudo replicas in meta-analysis [closed]

How do i control pseudo replicas in meta-analysis studies? I know I can randomize samples using Bootstrap for example, but how do I do this? Any clarification will be most welcome!
53 views

### Correcting for reliability scores for Hedges g

I've received a revise and resubmit on my meta-analysis investigating the effects of a positive psychology intervention on depression and anxiety symptoms. I used Hedges' g as the effect size within a ...
33 views

### Summary effect size of multiple dependent effect sizes

Problem Statement I am currently conducting a meta-analysis. At the moment, I am just calculating the effect size for each included study (for our purpose we chose the correlation coefficient r). ...
44 views

### Can multilevel meta analysis be random-effects model and/or fixed effects model?

I am learning multilevel meta-analysis (or, three-level meta-analysis e.g., https://bookdown.org/MathiasHarrer/...
46 views

### Pooled analysis of studies with only intervention arm

I want to perform a pooled analysis of studies including only a treatment arm, so no proper control groups are available. Studies present data about subjects before the treatment and after treatment, ...
295 views

### How to convert beta from logistic regression into cohen's d?

Is there a way to transform a coefficient from a logistic regression into a cohen's d value? I am trying to calculate the cohen's d for a study with a binary DV while controlling for another ...
40 views

### How to convert sampling sampling variances for a meta-analysis using raw means as effect sizes?

I am conducting a meta-analysis using raw mean scores as effect sizes (i.e., reported test scores on a certain standardized test). I found a calculation formula for sampling variances provided by, e....
93 views

### Meta-analyses using raw mean as Effect Size, instead of mean differences (e.g., Cohen's d)

I am writing up my meta-analysis using raw mean scores as effect sizes (i.e., reported mean scores on a certain standardized test) using the metafor package in R. ...
21 views

### Trelllis plots in meta-analsysis [closed]

I am trying to plot, a trellis plot. But I get an error and I don't know what its means. ...
24 views

### Multilevel regression meta-analysis : no existing package? (Edited)

The question is in the title. Meta-analysis with binomial distribution I'm trying to do a meta-analysis on occurence of an event across different studies. For each study $i$ ($i=1,\dots,N$), I have ...
15 views

### How do I use clinical trials as random effects in a cox regression model stratified according to trial for an individual patient data meta-analysis? [closed]

I am performing an individual patient data meta-analysis and pooling several trials. I have the data all combined in a single data set and want to fit it in a Cox regression model stratified according ...
43 views

### Prediction Intervals by meta package

I am using meta 4.9-5 package for conducting meta-analysis on correlation data. But I cannot figure out why it is unable to calculate lower and upper prediction intervals even I have set prediction = ...
66 views

### How to handle studies that don’t provide an estimate of effect size in a meta-analysis?

Say we want to survey the literature to find out the effect of Treatment A on Value B. Some studies provide an effect size estimate with confidence intervals and t-test results (e.g., “Treatment A ...
37 views

### Predicting disease based on eeg electrode power features and source power estimates

The dataset consists of Eeg electrode power features in all power bands(alpha, beta, delta..both relative and absolute) and source power features (obtained after source estimation) in addition to ...
51 views

### Why is Metafor R package giving an I2 for fixed effects meta-analysis model (rma.uni)? [closed]

I'm trying to run a fixed effects meta-analysis using the Metafor R package and in the documentation I read that it does not return an I^2 for fixed effects models, only for random effects models. ...
183 views

### Are there good alternatives to Cochran's Q test for heterogeneity in meta-analysis?

We used the Q test to determine heterogeneity with p-values <0.10. A highly recognised statistician commented that the Q test has low power and that it should not be used to determine presence of ...
33 views

### Regression multi-level meta-analysis with binomial data in R: no existing package? [closed]

The question is in the title. Meta-analysis with binomial distribution I'm trying to do a meta-analysis on occurence of an event across different studies. For each study $i$ ($i=1,\dots,N$), I have ...
50 views

### What's the statistical method of comparing the amount of pre-post difference scores of between groups?

I am currentnly doing a meta-analysis of the effects of social cognitive training on social cognitive function of patients of schizophrenia. There are wo conditions: treatment group receving social ...
54 views

### model test p-value>0.05 but intrcpt <0.05 [closed]

Mixed-Effects Model (k = 21; tau^2 estimator: SJ) tau^2 (estimated amount of residual heterogeneity): 0.2301 (SE = 0.0752) tau (square root of estimated tau^2 value): 0.4797 I^2 (...
37 views

### Assembling meta-analysis data with paired data for metafor

I am trying to assemble a meta-analytic dataset for computing yi and vi for metafor. For this dataset, I am including paired data (i.e., one sample of participants that completed upright and inverted ...
93 views

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### Variance–covariance matrix in meta-analysis of variation metafor

I'm conducting a meta-analysis on estimating a gold standard measure from other simpler measures. To determine the error of estimation, I derived the standard deviations of the differences between the ...
88 views

### What methods could be used to determine the validity of results from meta analysis besides conflict of interest?

Based on the answers I've read to a question1 on the Skeptics stack exchange, I began to wonder what methods besides the declaration of industry funding could be used to determine the validity of ...
48 views

### Help with meta-regression

I want to implement a meta-regression and require some assistance. Suppose that two univariate features ($X$ and $Y$) were measured from two samples $A$ and $B$ of size $N_A$ and $N_B$, respectively. ...
40 views

### metafor for incidence rates - how to calculate relative risks and 95% CI's

I'm very new to the metafor package and wanted to check my interpretation of the model output, specifically in regards to calculating relative risks and confidence intervals. I've used the rma.mv() ...
48 views

### interpreting meta regression results in R

I performed meta-regression in R and got the following results: Mixed-Effects Model (k = 21; tau^2 estimator: ML) ...
83 views

### Meta-analysis with random effects on prevalence data with > 2 possible outcomes: is it necessary that the weighted prevalences all add up to 100?

I am running a meta analysis on prevalence data. Participants can belong to one of four groups. Each study produces the percentage of participants that belong to each group (e.g., Group A: 50%; Group ...
43 views

### SMD meta-analysis including cluster-randomised trials: is it possible? If so, how?

Where we have cluster-adjusted results from trials (summary statistics), under what circumstances can we include them in a standardised mean difference (SMD) meta-analysis and which calculations are ...
662 views

### Effect size calculation for Kruskal-Wallis mean rank test

I have a published paper in which I'm attempting to calculate the effect sizes for various outcomes. For a pre-post scale, the authors report the sample size, mean rank, and p-value for an outcome (...
34 views

### Covariance structure of effects in multivariate meta-analysis with correlated outcomes and predictors

I'm working on a meta-analysis of studies examining the correlation between SES and mental health. Unfortunately, studies typically have multiple measures of both SES and mental health, which I've ...
26 views

### Is it possible to “sample size weight” the effects of multiple regressors to that of a “big” regressor? [duplicate]

I know that you can't just take averages and state that it is the average effect of the big regressor (Simpson's paradox). But I would be interested in knowing wether you could state that a positive ...
13 views

### Checking association between each category of a variable and disease outcome

Suppose a disease can have four different outcomes: Normal, disease_status_1, disease_status_2, and disease_status_3. Let I have two categorical variables in the model: sex (male or female) and age (&...
25 views

### identifying what has changed in the data year on year

I have a dataset from one year and the 'same' dataset for the next year. I would like to identify what has changed in the datasets between the years. Both datasets have the same columns. I currently ...
48 views

### Meta-analyzing ICCs to avoid using multiple random effects?

(Note: Parts where I've encountered problems are in bold to make them easily findable.) I have data from a longitudinal study of twins. Several biomarkers are measured, usually 4 measurements each (...
141 views

### Clustering and interactions in a multilevel model in R

We are conducting an individual participant level meta-analysis on a series of clustered randomised controlled trials, where we are mainly interested in an interaction effect with a characteristic (...
37 views

### d to r conversion for extremely high versus extremely low groups

Context Suppose I am performing a meta-analysis on the relationship between two variables (say depression and life satisfaction). Unfortunately, many studies in the prior literature do not report ...
74 views

### conducting a meta-analysis on pre-post control design studies that use count data

I would like to conduct a meta-analysis on a set of studies that have measured an outcome over a period prior to intervention and post-intervention for a control group and experimental group. A method ...
17 views

### Meta-analysis for case-control studies, confounding factors

Is there a way to adjust the pooled summary effect size (odds ratio) for confounding factors while performing a meta-analysis in R studio? I am performing a meta-analysis and I don't want to pool ...
41 views

### Re: Random Effect Model in Binomial Proportions Meta-analysis

I have used a random effects model for the meta-analysis of binomial proportions and have encountered several queries. In one meta-analysis, I have four studies. Sample size of 98, 58, 107, 62 ...
39 views

### How can I calculate z-value from chi-squre distribution with 2 df? [closed]

I tested two models and one is nested inside another. Nested model has 2 parameters and the bigger model has 4. I got the ln likelihood of each models. I know how to calculate the P value using twice ...