Questions tagged [meta-regression]

A meta-analytic tool that examines the impact of moderator variables on studies' effect size. It is another name for mixed effects model in meta-analysis (moderators are fixed effects, studies are random effects).

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Adding a covariate to a meta-regression with low sample size

In an meta-regression I am working on an interesting question has come up. I am are running a meta-regression with 32 study sites. I have four theoretically motivated covariates I want to examine. ...
20 views

Meta Regression- Average AGe

I want to conduct a meta-regression, using the variable. The studies in my meta-analysis include studies, that compore two indipendent groups. My question: to calculate average age of a study - is it ...
40 views

Formulas for multivariate meta-regression

everyone! I'm digging in meta-regression and doing hand calculations using WLS to get better understanding of the topic. I'm fine with calculations for univariative model (that is, 1 covariate is ...
22 views

Can multilevel meta analysis be random-effects model and/or fixed effects model?

I am learning multilevel meta-analysis (or, three-level meta-analysis e.g., https://bookdown.org/MathiasHarrer/...
50 views

model test p-value>0.05 but intrcpt <0.05 [closed]

Mixed-Effects Model (k = 21; tau^2 estimator: SJ) tau^2 (estimated amount of residual heterogeneity): 0.2301 (SE = 0.0752) tau (square root of estimated tau^2 value): 0.4797 I^2 (...
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Help with meta-regression

I want to implement a meta-regression and require some assistance. Suppose that two univariate features ($X$ and $Y$) were measured from two samples $A$ and $B$ of size $N_A$ and $N_B$, respectively. ...
43 views

interpreting meta regression results in R

I performed meta-regression in R and got the following results: Mixed-Effects Model (k = 21; tau^2 estimator: ML) ...
60 views

Is it possible to meta-analyze means on different scales?

I have study-level means/SDs reflecting depression symptom severity from multiple single-group studies. I do not have access to participant-level data. The studies all use different measures, and I ...
48 views

meta-regression using metafor

How should I syntax the rma function from metafor package in order to get results in the following example? My objective is to compare values (means) among species. I have different papers ...
24 views

Meta-analyzing means/SDs from repeated-measures studies

I'm working on a meta analysis of prospective studies assessing changes to mental health in the year following an event. For the purposes of example, say it's the severity of depressive symptoms (...
49 views

Meta-analyzing rates of change in one variable observed in one group over time

I'm working on a meta analysis of prospective studies assessing changes to mental health in the year following an event. For the purposes of example, say it's the prevalence of major depressive ...
61 views

Regularization techniques (ridge, lasso or elastic-net regression) for meta-analysis

I was perusing the StatQuest YouTube channel, and serendipitously listened to a series of videos on regularization techniques (ridge, lasso or elastic-net regression). It came to my mind that such ...
80 views

Use of nested random terms in meta-analysis with a moderator

I am conducting a meta-analysis and I am struggling with the random structure when there is a continuous moderator and a nested random term. Starting with a simple example: ...
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127 views

Calculate sample variances from linear regression model for meta analysis?

I want to perform a meta analysis in two levels using linear regression in R (with lm() ). I understand that in the second level I should perform a weighted ...
60 views

How to meta-analyze three effect sizes of correlations?

I am searching statistical approaches to analyze three effect sizes of correlations. I would like to see the relationships among one independent variable (performance on a certain type of cognitive ...
43 views

How can I perform bivariate random-effects meta-regression if the implied between-study covariance matrix is not positive definite?

I have described my problem here: How can one get consistent (i.e. direct+indirect=total) effects in a Meta-Analytic SEM model with latent variables? Unfortunately, the solution I've found to this ...
113 views

Output of metafor for incidence rates

I need to clarify something and am hoping Wolfgang or someone else with expertise in the metafor R package could help. I want to know what the output of the rma model (with a moderator in is for a ...
37 views

Assessing normality assumption of effect sizes in meta-regression

I'm considering options for estimating tau-squared (the true between-study variance) in meta-regression, and I know method-of-moments (MM), unrestricted maximum likelihood (ML) and restricted maximum ...
29 views

If someone wanted to do a meta analysis would they be able to use a publication that does not have p-values listed in the publication?

If someone wanted to do a meta analysis would they be able to use a publication that does not have p-values listed in the publication? Does a meta analysis really need a publication to have a p-value?...
71 views

Test whether effect size in meta-analysis is significant when controlling for moderator

I am using the metafor package to conduct a meta-analysis. I’d like to test whether the overall effect size is significantly different from zero when controlling ...
36 views

Comparing predictions from multilevel meta-regression model

I'm using the metafor package in R to perform a multi-level meta-regression. I did not supply a variance-covariance matrix to the ...
350 views

Moderator Analysis in meta-analysis in metafor package - conceptual questions [closed]

I am a beginner in statistics and currently have to conduct a meta-analysis in my lab. I am facing some difficulties to understand the meta-regression. I read this webpage and tried to follow along: ...
33 views

Is there a test error metric that takes into account variance of the data?

In standard machine learning applications, models are often evaluated based on metrics like RMSE or Deviance. I was wondering if there is a similar metric tailored towards meta-analyses that takes ...
272 views

Diagnostic residuals for Beta GLMM weighted by sample size (Meta-analysis) using glmmTMB

I am conducting a GLMM for a meta-analysis using the beta distribution with the package glmmTMB. My response variable is a vector of correlations (No exact 0 or 1), but Fisher’s transformation fails ...
112 views

Multiple categorical IVs in meta-regression

I'm running a meta-regression and am inputting at different study characteristics as IV's. The problem is some are continuous and some are categorical. The IV's are: Age Gender (2 values, dummy coded) ...
69 views

Effect size for meta-regression

I have conducted a hierarchical meta-regression, and the results revealed a large R2 with all predictors in the model, which is common in meta-regressions. Some of the non-significant results might be ...
70 views

Why am I getting different means when conducting multilevel meta-analysis with factorial moderator vs. as subgroups?

I already asked about this in stackoverflow but maybe it fits better here. I want to conduct a multilevel meta-analysis using metafor in R. I have effect sizes ("esid") nested within samples ("...
605 views

Meta-analysis of proportions - how to analyze possible moderators and publication bias?

I am performing a meta-analysis study of proportions in Stata using the metaprop command. My data includes 10 studies for which I have the variables: ...
289 views

Do I need to know correlations between dependent effect sizes for multilevel meta-analysis?

I am meta-analyzing with multiple effect sizes from each study. The studies included in my meta-analysis measured the effects of participants REPEATDLY with MULTIPLE TESTS. I am trying to deal with ...
27 views

Averaging ES from the same study in a MA

I'm completing a meta-analysis looking for an effect size for rates of forgetting for people with epilepsy vs controls. I've already decided to separately extract effect size for the verbal and non ...
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How would I conduct a relative risk meta-analysis, when the exposure levels in the data are presented in overlapping ranges?

For example, if I have studies observing the dose-response relationship between alcohol (g/day) and breast cancer, and the exposures are reported as heterogeneous and overlapping ranges (10-20g, 15-...
424 views

Easy post-hoc tests when meta-analyzing with the metafor package in r

I am conducting meta-analysis using metafor in R. I would like to compare among 7 levels in a factor (i.e. different types of treatments). ...
413 views

Step-wise Bayesian updating as a prior selection strategy

There is a famous principle in Bayesian that says: 'Yesterday’s posterior is today’s prior'. Lindley (2000). Now, suppose there are three studies conducted chronologically. Based on Lindley's (2000) ...
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Is my full model with all significant estimates really the most parsimonious model?

I am performing a model selection based on BIC (Bayesian information criterion). I start with the following model fitted with rma.mv() in the 'metafor' package: ...
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Is it possible to do multiple regression on participants' level variables across studies using meta-analysis aggregated data? [closed]

I am wondering is it possible (or appropriate) to perform multiple regression using participants level variables across studies using meta-analysis data? I know that usually, meta-regression is ...
384 views

Meta-regression using rma from metafor, using DL random effects, with same effect for studies with same id

I would like to run a meta-regression on my dataset using DerSimonian-Laird (DL) random-effects model. For some studies in my dataset, I have more than one datapoint. Therefore, I would like to ...
1k views

Interpreting meta-regression outputs from metafor package

I have been using the metafor package for some meta-analyses and would like to adjust for a single continuous covariate (mean age) using meta-regression. However, I require some clarification ...
264 views

Logit transformation for a meta-analysis

I am in the final stages of a meta-regression on disease prevalence data and potentially associated covariates. I've entered the data as raw proportions and am using the logit transformed event rate ...
442 views

Interpreting and plot interactions between continuous variables in rma.mv ('metafor') outputs

I was looking for ecologically-meaningful interactions in mixed-effects models of my meta-analysis when something nice (or at least I think!) came out. My meta-analysis looks at plant diversity (i.e<...
154 views

Underlying computing methods for meta-regression in the metafor package and the meta package

I was conducting a meta-analysis of single proportions(i.e. without a control group) and was trying to perform a meta-regression on a moderator in my data set (lable:modb) using two different R ...
156 views

Backward model selection in metanalysis using 'glmulti' and/or 'metafor'

I want to test with a full model testing significant interactions with the main predictor 'Nadd' for my log transformed response ratio (...
713 views

Meta-regression of a single-arm study with proportion outcome in R

I'm trying to understand how to perform meta-regression treating each arm of studies in my data as an individual study with a single proportion as the outcome. I have read through the ...
297 views

Testing for interaction between subgroups across multiple trials - meta-analytical test for interactions

I've got 3 trials, A, B, C. These test drug X vs placebo, giving an HR for benefit of survival vs. placebo. There is a dichotomous subgroup analysis, for clarity let's say patients > 50 years old, ...
In a single study, a researcher can obtain a relevant summary statistic, and construct an $x$% confidence interval for that summary statistic. Under the frequentist framework, this obtained ...