Questions tagged [mortality]

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Can I use indirect standardization with the WHO Standard World Population?

I have to compare mortality rates among countries for a variable where the age-specific mortality rate is not available, but the overall rate is. I want to use indirect standardization with the WHO ...
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1answer
13 views

How to interpret log Relative Hazard?

Let's have two groups, A and B, and let's assume that A is a reference in Cox model and B has two times higher hazard to die at a certain time point, Hazard Ratio = 2. But what is log Relative Hazard ...
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1answer
31 views

Ideas and good practices for reporting crude survival trends?

I have 9-year-spanning data on patients survival (n = 10000). Each patient has a date of inclusion (got a diagnosis), which was used to determine the year of inclusion. Thus, temporal trends can be ...
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1answer
12 views

Which test should be used to compare crude mortality between 15 groups?

I have fifteen groups (factor levels) and I need to compare their crude mortality. Is Logrank test limited to two groups only? Which test would be correct to use in this case?
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59 views

Poisson regression for modeling standardized mortality ratio (SMR)

I have a data set with individuals with a certain diagnosis who are observed from the time of their diagnosis until death or the end date of the study. I want to calculate SMR for the whole group, and ...
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1answer
81 views

Is this a correct way to confirm Accelerated Failure Time (AFT) method's suitability for analysis? An example

I need to conduct an adjusted survival analysis, however, Cox PH assumption was not met and data stratification isn't a good solution as one of my study groups already has a small number of patients. ...
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1answer
65 views

Recent mortality [closed]

Recently there are a lot of datapoints regarding COVID-19 related deaths. However I am looking to see how big the impact of non-diagnosed patients is. Therefore I want to evaluate the deaths (...
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1answer
107 views

Is there a model to predict mortality rate of an ongoing epidemic?

Following the recent Coronavirus outbreak, various mortality rates have been published. Most of these are simply the ratio between the deaths and the total verified cases, which is not a very ...
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106 views

How to calculate mortality probability using SOFA, APACHE, SAPS score?

I'd like to use SOFA score to get AUC of mortality. As I know, it should have the mortality probability first so that I can get AUC. However, I am not able to find the formula to convert SOFA score ...
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19 views

Extension of Lee-Carter model with parametric functions of age and time

A standard model of mortality is the Lee-Carter model where Deaths at age $x$ and time $t$ are given by $D_{xt}\sim Poisson(E_{xt}\mu{xt})$. $E_{xt}$ and $\mu_{xt}$ are, respectively, the average ...
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36 views

Cut off age for mortality data

I have data with death rates for each year 1921 to 2014; and for each age 0 to 110 as below: ...
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46 views

Lee Carter mortality model - OLS (SVD) estimators if errors are heteroscedastic

In the classical Lee-Carter model, central death rates are modelled as follows: $\log(m(x,t)) = a(x) + b(x)\kappa(t) +\varepsilon(x,t)$ for some $x=0,\ldots,\omega$ and $t=1,\ldots, T$ and where $a(...
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83 views

How do I calculate standard error for mortality experiment?

I ran an experiment looking if injuries affect the mortality of crabs over 50 days. How do I calculate the standard error for days when crabs died in relation to the percent mortality? Say I start ...
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2answers
95 views

Cox regression different results with different combinations of variables

I need help understanding how to use cox hazzard model to calculate risk of death in data from a cohort study. I have a set of data on physical activity and I want to do a cox regression on ...
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1answer
67 views

How to plot mortality at age curve using lifespan data

I have a table with the lifespan of multiple individuals from a species and would like to use this data to plot a mortality rate curve, similar to that shown in figure 1 of this study:https://www....
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96 views

R - matrix optimization problem (Lee-Carter with MLE parameters)

I am trying to reproduce one of models evolved on the base of Lee-Carter model by use of RStudio. Because I am still pretty fresh in this software, my question is not really sophisticated. Applying ...
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187 views

Comparison of extrapolated kaplan-meier survival curve with background mortality

For my research I am doing an health economic assessment of patients with a renal transplant. For my model I need to know their (yearly) mortality probability. My plan was to extrapolate survival data ...
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1answer
28 views

How do I determine if the difference between treatment and control is significant when they have different sample sizes?

I am currently performing a test in C. elegans mortality. In my extract and negative control, different sample sizes of worms (25-30 worms) were used due to the degree of difficulty of transferring ...
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242 views

r - Poor model fit with StMoMo package on Human Mortality Database

I am fitting USA mortality data from Human Mortality Database (with data downloaded from here after registering for a free account https://www.mortality.org/cgi-bin/hmd/hmd_download.php) with the ...
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26 views

Mortality rates - can multiple (overlapping) categories with <20 events be combined?

I'm trying to track trends in alcohol/tobacco/drug related deaths for a small, rural county. I have some locally produced stats where they seem to just add the relatively few alcohol and drug related ...
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1answer
70 views

How to define the Lee-Carter model and its constrains in Bayesian setting

I'm running the Bayesian version of Lee-Carter model on jags, using rjags R package. Given a matrix of data $M$ such that $M_{x,t}=\log m_x(t)$ where $m_x(t)$ is ...
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98 views

Convert “Alive” counts per replicate and time to survival data

I have a raw data set describing survival in groups of individuals over time, organized as follows: ...
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1answer
221 views

Converting annual to daily mortality rate

In one excel workbook I am working on right now, the annual mortality rate is given as 3.082% And the formula for calculating the daily mortality rate is 1-EXP(LN(1-[annual mortality rate]/365) Why ...
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91 views

Right-censored cash flows and survival analysis

I am doing survival analysis on a disability claims dataset - each row tells me how long a person has been on claim and whether they have gone off claim yet. Ultimately I am interested in predicting ...
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1answer
98 views

Calculating Expected Number of Deaths from Life Tables

Normally, if analysing cohort data, I would expand on time using the Lexis macro (if using SAS) and then calculate the expected number of deaths as the life table central mortality rate (mx) matched ...
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150 views

How can I compare two standard mortality ratios (SMRs)? [duplicate]

I have a population who I separated into three groups: low, medium, high exposure. I calculated the standard mortality ratios (SMRs) for each of this group using a standard population. One of my ...
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1answer
2k views

What is the best statistical test to compare mortality rates between 2 groups?

I want to compare the mortality rates of 2 groups (control vs treatment). I have binary data (1 = Alive ; 0 = Dead) which gives me a mortality rate (%). What is the best way to compare these 2 ...
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1answer
280 views

Excess Mortality versus Relative Mortality

I have modeled the relative mortality of a US cancer cohort, but I want to apply the results to a cohort from the UK (this is the best option as there was no available UK data). Initially I thought ...
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1answer
74 views

Is there a way to set the desired range of an imputation algorithm?

Goal: I am interested to learn if there is a way to set the range of an imputation algorithm for Missing Not at Random (NMAR) data, such as Multiple Imputation or Maximum Likelihood Estimation. ...
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1answer
456 views

analyzing binary mortality data collected at different remeasurement intervals. Bonus for R implementation

I am replicating an analysis that models tree mortality data. Data are structured such that forest sites are revisted at some random interval, which is recorded. It is then determined if a tree lived ...
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2answers
639 views

Logistic or Poisson Regression for Mortality Modelling?

I am attempting to model the probability of death while controlling for a number of other variables. I began to do this with standard logistic regression, but I've come across a number of articles ...
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31 views

Would a contingency $\chi^2$ test be useful in this case?

I am looking at mortality of caterpillars who were reared on different diets. I have the total number of caterpillars on each diet on the first day of observation, and then again on the final day of ...
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30 views

Crude death rate per 100 subjects per year with missing values and different lengths of follow-up

We need to compute the crude death rate per 100 subjects per year. We have a dataset with 383 observations. The death status is available for every subject, but the length of follow up is different ...
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59 views

Does this analysis make sense and can anyone provide relevent references?

I have a GEE logistic regression model that I've built that predicts that probability of mortality given a rather extensive set of covariates. I wanted to write here as a sanity check of sorts to ...
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1answer
257 views

Parametric Bootstrap without model refitting?

I have a GLM poisson model that makes predictions of the probability of death for every observation in my dataset after fitting the model. I then take the sum or mean of these probabilities to obtain ...
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1answer
122 views

Using IMD in Statistical Models of Mortality

It is common in the world of health to incorporate measures of socioeconomic deprivation into statistical models. One commonly used proxy-measure of deprivation is the UK's Indices of Multiple ...
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1answer
7k views

Calculating force of mortality from life table

The force of mortality at age $x+t$, given survival to $x+t$ is given by $\mu_{x+t}$ $=-\frac{d}{dt}[ln({}_{t}p_{x})]$ Given a life table I know how to calculate ${}_{t}p_{x}$, but then how can I ...
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1k views

Modelling a binary outcome when census interval varies

For a current piece of work I’m trying to model the probability of tree death for beech trees in a woodland in the UK. I have records of whether trees were alive or dead for 3 different census periods ...
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1answer
79 views

Combining Force of Mortality for F and M to find $l_x$

So I have the definition of the force of mortality as $\mu_x=-\frac{1}{l_x}\frac{d l_x}{dx}$ and I am given two different forces of mortality, one for females as $\mu_x^f=0.05(1.2)^x$ and the other ...
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2answers
714 views

Hypothesis testing of two standard mortality ratios

Probably this is an easy question, but I don’t seem to find an answer. The standard mortality ratio (SMR) is defined as “the ratio of actual number of deaths in the group under study to the expected ...