# Questions tagged [mortality]

Use for studies investigating mortality and related topics like life-tables and life expectancy.

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28 views

### Calculating death rates for an increasing population over the long-term

I'm part of a small long-term outcomes study for a specific MH intervention. We're becoming a little alarmed at the number of subjects who seem to have died in their 20s and we'd like to make sure ...
29 views

### Best test for mortality rate in two countries

We’re trying to compare the mortality rate in two different countries over a period of 20 years. Is the Mann Whitney u test the best to use? We’re confused if the data is assumed to be normally ...
195 views

### Question about combined relative risk interpretation

I am looking at a review of the effects of cigar smoking, and I am having trouble interpreting some of the results. Study linked here: Study Specifically I have questions about table 3, below: In the ...
1 vote
48 views

### Pooled Hazard Ratio or Crude events (M-H to RR or OR) for mortality outcomes in Meta-Analysis?

I'm performing a MA to estimate the effect of treatment A respect to Placebo (or propensity-matched control group) respect to all-cause death. All the studies included in my MA report both crude ...
26 views

### Assessing deviations between actual and expected mortality rates with GAM models and confidence intervals

I'm currently using a Generalized Additive Model (GAM) aimed at modelling mortality as a binary response (1 if the person has died and 0 otherwise). My primary goal is to compare the actual mortality ...
85 views

### Which models are available to estimate relative life expectancy (in years, not in hazard ratios)?

I have a well-phenotyped survival dataset (i.e. it has a high number of relevant covariates for a study of mortality) for which I estimate how certain conditions influence life expectancy (LE). It ...
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41 views

### Which test do I need for testing differences in two populations?

I would like to compare the different variables in a life table of two populations and check if the differences are significant. However, I am totally unsure which test is appropriate. For example, I ...
84 views

### Can I claim that the relative risk of age effect in Poisson regression is a mortality rate?

Suppose I run a poisson regression with yearly death count as outcome: $\log \mu_{t}=a + \beta_{ti} \kappa_{ti} + offset$ $\mu_{t}$ refers to the number of death at time $t$; $a$ refers to intercept; \$...
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31 views

### What Glmm method is best to analize Mortality Rate as a response variable

I am investigating the effect of two explanatory variables (one continuous and one binary) on my continuous response variable (Mortality rate). This variable is a proportion and resembles a gamma ...
39 views

### Difference between Mortality Rate, Crude Death Rate and Cause-Specific Death Rate

Like the title explains, I'm having a difficulty understanding the differences between: Mortality Rate Crude Death Rate Cause-Specific Death Rate. Somebody please explain the differences.
35 views

### Comparing Age-Adjusted Mortality Rate between 2 groups

Context: I am using national mortality database to compare the mortality of X disease by demographic factors. I divided the county based on social vulnerability scoring into 4 groups (1,2,3,4 based on ...
27 views

### Combining cause-specific mortality cox regressions into all-cause mortality

I only have access to the following dataset summary data and not to the dataset itself. In the example, the stats on each line come from a univariate cox regression to model a cause-specific ...
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1 vote
47 views

### Meta analysis of generic inverse variance [closed]

I'm doing a a meta analysis on the mortality of heart failure patients and I'm using hazard ratios reported in the studies for the meta-analysis using REVMAN software. All of the hazard ratios and ...
• 11
1 vote
154 views

### Interpreting shape and rate parameters from a weibull model of mortality hazard in BaSTA

I am using the BaSTA package in R to estimate sex differences in survival parameters for a capture-recapture dataset. When I use a simple Gompertz model the parameters are very interpretable (b0 ...
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1 vote
15 views

### How to control for mortality in an assay with multiple tests and inconsistent control mortality results?

Some context : I work on insects and most of our tests are mortality assays : we subject groups of insects, in replicates (usually 5-6), to insecticides and record the mortality 24h later. Since we ...
• 51
1 vote
64 views

### Test of statistical significance for equality of two ratios rather than proportions

I have data from two sample surveys done on Maternal Mortality. At each survey, the number of live births and the number of maternal deaths have been recorded. I have calculated the Maternal Mortality ...
• 11
149 views

### Including exposures in logistic regression

I’m performing a logistic regression in Jupyter Notebook. My target is 1 if a subject died while under observation and 0 if the subject did not die. Not every subject was observed for the same period ...
15 views

### Can estimated values with wide confidence intervals be used calculate association or correlation coefficients?

I want to test for an association between socioeconomic deprivation and death rates. My data are raw death counts and deprivation ranks for a set of small geographic areas. Some areas have very low ...
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1 vote
16 views

### Should COVID excess mortality be corrected afterwards?

A widespread measure of effect of the COVID pandemic is the excess mortality. Two examples of methodologies to calculate are the calculations of the European Union statistics office and the Economist. ...
• 111
1 vote
168 views

### Using a log-poisson model to predict mortality

I'm trying to build a GLM in Python that uses a log-poisson model from the statsmodels package to predict mortality rates. I have a policy level dataset that, among other features, contains attained ...
• 11
747 views

### GLM with proportion data and two categorical predictor variables

I want to analyze data on mortality (as number of dead individuals in the total number of individuals) in function of treatment (two levels) and location (four levels). I’m also interested in the ...
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250 views

### Hessian not listed in GAM output of some models. Does this matter for significance of smooths and comparison with AIC?

Would really appreciate some help as I don't know how to proceed given my GAM results. I haven't had much luck getting answers to my GAM questions (not sure if there is something wrong with the way I ...
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1 vote
99 views

### Applications of Mortality Tables and Life Tables?

Recently, I showed my friend what Life Tables and Mortality Tables are (e.g. https://en.wikipedia.org/wiki/Life_table) - I tried to explain possible uses for these kinds of tables but my friend argued ...
406 views

### Motivating use of Bayesian splines in excess mortality estimation

I'm reading this paper estimating excess deaths induced by the pandemic. That is, roughly, it constructs a model to estimate how many deaths (from all causes) would have occurred if the pandemic had ...
39 views

### Prediction of mortality based on age before and after a certain event

I have data on about 320 people. I am trying to predict their mortality before and after a certain event. I tried to apply a logistic regression model using dead or alive as dependent variable and age-...
98 views

### Interpolation to account for heaping effect in mortality time series for regression analysis

I am trying to estimate the relationship between daily temperature and daily number of deaths (from all causes) for a specific location using time series regression. More specifically, using a DLNM, i....
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1 vote
386 views

### Independence in Poisson regression when used for rates estimation

I'm interested in using Poisson regression for estimating mortality rates. I've observations for a rather long period, and have to face the fact that covariates often vary over time. This is ...
42 views

### Statistical test for probability of survival across different doses [closed]

I have 8 different doses of a chemical and the mortality rate of each group exposed to the chemical. I want to compare the probability of survival across various doses. What sort of statistical ...
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773 views

### How to get beta coefficients for reference group in Cox proportional hazards regression model survival analysis (R or other)?

The model was calculated using the coxph and survival functions from the survival package (R). Each of nine variables was set as categorical with a reference strata.The criterion was the survival ...
71 views

### Why does Covid19 confirmed deaths lag behind all causes deaths?

It appears that Covid19 confirmed deaths dates lag about 10 days behind the all causes deaths. This is at least true in European countries (I didn't check this elsewhere) and is particularly obvious ...
26 views

### Log-rank test: should I run it once for the whole follow-up or also test for shorter time periods?

Let's assume we have a 5-year follow-up for survival for two groups, and I report their crude mortality rates for years 1, 2, 3, 4 and 5. After that, would it be reasonable to test the mortality ...
1 vote
22 views

### Which control charts to use to track mortality

I am trying to implement control charts in my organization (healthcare) to track various quality outcomes. The first one i want to do is mortality( # patient deaths/ month(or week) ). I have a data ...
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1 vote
76 views

### Cox mode: PH violated because of multiple covariates

I have a cox model as follows, comparing survival of 5 subgroups (one is always a reference). Data is relatively large as n = 12 000; however, the sizes of the subgroups range from 60 to 9000 subjects....
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1 vote
12 views

### Reporting relative adjusted survival between categorical predictor's levels

I'm looking for an option for reporting relative survival between categorical predictors' levels. It would very easy with Cox regression; however, I am using an AFT model as the proportional hazards ...
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107 views

### Interpreting the summaries of survival models with different distributions (flexsurvreg R package)

I run several flexsurvreg models with the same predictors and now struggle to interpret their findings in an understandable plain language. Males seem to have lower survival in all models, but the ...
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1 vote
57 views

### Analyzing survival: meaningful to report estimates for different time periods with Cox and AFT?

I am trying to figure out the following. Could you please comment on this? Goal is to compare survival between two groups. Let's assume we have data with one-year follow up and have a simple model for ...
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1 vote
45 views

### Comparing the discriminative ability of two comorbidity indices for mortality: should I go for ROC and AUC?

Different comorbidity indices are widely used tools for describing patients' comorbidity statuses. A large score = many illnesses, and vice versa. I would like to compare two such indices to examine ...
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1 vote
346 views

### Interpreting mortality trends shown as relative hazard

I am analysing trends in survival. I was recommended to use the following package and parameterization. I have a model as follows (done with rms package): ...
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754 views

### Assessing non-proportional hazards when proportional hazards assumption is violated

Could you help me to proceed with a request by a reviewer? I have a Cox model like this time_1year | status ~ p1 + p2 + p3 + p4 I was not able to perform Cox regression at 2 year as the proportional ...
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33 views

### How to get the number of deaths per month in this dataset?

This dataset shows the number of deaths (of all causes) in the US in 2019. It's labeled in weeks. What is the right interpretation of this for getting the number of deaths in January? Should I add ...
252 views

### Confidence interval for Standardized Mortality Ratio

So in a number of places, for example here, I've seen stated without explanation that the standard error of the SMR (at 95% confidence threshold) is simply $$SE_{SMR} = 1.96 * \frac{\sqrt O}{E}$$ ...
1 vote
56 views

### How can both life expectancy and death rate increase over 70 years time for a country?

I see death rate and life expectancy for Greece. For the first there is a constant growth from 1994 which is envisaged to grow up to 2068. For the latter there is a constant grown from 1950 which is ...
240 views

### Covid-19 and life expectancy

A public figure in my home country said the following: "The life expectancy in our country is 82 years. The average age of those who die of covid-19 is also about 82 years. Hence, on average, ...
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3k views

### Why does the US death rate not "match" life expectancy

From the CDC (https://www.cdc.gov/nchs/fastats/deaths.htm): Death rate: 863.8 deaths per 100,000 population Life expectancy: 78.6 years Now in a static situation I ...
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97 views

### Can I use indirect standardization with the WHO Standard World Population?

I have to compare mortality rates among countries for a variable where the age-specific mortality rate is not available, but the overall rate is. I want to use indirect standardization with the WHO ...
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1 vote
1k views

### How to interpret log Relative Hazard?

Let's have two groups, A and B, and let's assume that A is a reference in Cox model and B has two times higher hazard to die at a certain time point, Hazard Ratio = 2. But what is log Relative Hazard ...
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63 views

### Ideas and good practices for reporting crude survival trends?

I have 9-year-spanning data on patients survival (n = 10000). Each patient has a date of inclusion (got a diagnosis), which was used to determine the year of inclusion. Thus, temporal trends can be ...
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47 views

### Which test should be used to compare crude mortality between 15 groups?

I have fifteen groups (factor levels) and I need to compare their crude mortality. Is Logrank test limited to two groups only? Which test would be correct to use in this case?
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1k views

### Poisson regression for modeling standardized mortality ratio (SMR)

I have a data set with individuals with a certain diagnosis who are observed from the time of their diagnosis until death or the end date of the study. I want to calculate SMR for the whole group, and ...
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