Questions tagged [mortality]

Use for studies investigating mortality and related topics like life-tables and life expectancy.

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17 views

gnm algorithm with Lee-Carter?

To fit population and deaths data to the Lee Carter model using Poisson assumption Lee carter model , I make use of the package StMoMo. I wonder what the ...
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5 views

How can mortality rate of a cohort population be converted to a +/- number of months or years from average life expectancy?

How can mortality rate of a cohort population (eg: 65/1000 annually for those who smoke 1 pack per day) be converted to a plus or minus number of months or years from average life expectancy, as seen ...
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23 views

Cox mode: PH violated because of multiple covariates

I have a cox model as follows, comparing survival of 5 subgroups (one is always a reference). Data is relatively large as n = 12 000; however, the sizes of the subgroups range from 60 to 9000 subjects....
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6 views

Reporting relative adjusted survival between categorical predictor's levels

I'm looking for an option for reporting relative survival between categorical predictors' levels. It would very easy with Cox regression; however, I am using an AFT model as the proportional hazards ...
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7 views

Interpreting the summaries of survival models with different distributions (flexsurvreg R package)

I run several flexsurvreg models with the same predictors and now struggle to interpret their findings in an understandable plain language. Males seem to have lower survival in all models, but the ...
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1answer
18 views

Analyzing survival: meaningful to report estimates for different time periods with Cox and AFT?

I am trying to figure out the following. Could you please comment on this? Goal is to compare survival between two groups. Let's assume we have data with one-year follow up and have a simple model for ...
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1answer
28 views

Comparing the discriminative ability of two comorbidity indices for mortality: should I go for ROC and AUC?

Different comorbidity indices are widely used tools for describing patients' comorbidity statuses. A large score = many illnesses, and vice versa. I would like to compare two such indices to examine ...
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1answer
22 views

Interpreting mortality trends shown as relative hazard

I am analysing trends in survival. I was recommended to use the following package and parameterization. I have a model as follows (done with rms package): ...
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25 views

How to simulate deaths using life/mortality table data?

I am writing a simulation that utilizes mortality tables to determine, at each step of the simulation, the members of the simulation that should die (or "expire", if you prefer). I believe ...
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1answer
43 views

Assessing non-proportional hazards when proportional hazards assumption is violated

Could you help me to proceed with a request by a reviewer? I have a Cox model like this time_1year | status ~ p1 + p2 + p3 + p4 I was not able to perform Cox regression at 2 year as the proportional ...
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28 views

How to get the number of deaths per month in this dataset?

This dataset shows the number of deaths (of all causes) in the US in 2019. It's labeled in weeks. What is the right interpretation of this for getting the number of deaths in January? Should I add ...
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15 views

How to determine if a list has been ranked on some criterion?

I have a list of a few hundred individuals and two methods which claim to rank the list in descending order of probability of mortality. I also have data to show whether death occurred within a set ...
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25 views

Confidence interval for Standardized Mortality Ratio

So in a number of places, for example here, I've seen stated without explanation that the standard error of the SMR (at 95% confidence threshold) is simply $$ SE_{SMR} = 1.96 * \frac{\sqrt O}{E} $$ ...
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11 views

Compare MIR (Mortality Incidence ratio) for three time periods

I have MIR data for 3 time periods, lets say 1995-1999, 2004-2008, 2014-2018 which i need to test statistically if they are significantly different from each other.
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45 views

How can both life expectancy and death rate increase over 70 years time for a country?

I see death rate and life expectancy for Greece. For the first there is a constant growth from 1994 which is envisaged to grow up to 2068. For the latter there is a constant grown from 1950 which is ...
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4answers
166 views

Covid-19 and life expectancy

A public figure in my home country said the following: "The life expectancy in our country is 82 years. The average age of those who die of covid-19 is also about 82 years. Hence, on average, ...
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3k views

Why does the US death rate not “match” life expectancy

From the CDC (https://www.cdc.gov/nchs/fastats/deaths.htm): Death rate: 863.8 deaths per 100,000 population Life expectancy: 78.6 years Now in a static situation I ...
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1answer
28 views

Can I use indirect standardization with the WHO Standard World Population?

I have to compare mortality rates among countries for a variable where the age-specific mortality rate is not available, but the overall rate is. I want to use indirect standardization with the WHO ...
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1answer
113 views

How to interpret log Relative Hazard?

Let's have two groups, A and B, and let's assume that A is a reference in Cox model and B has two times higher hazard to die at a certain time point, Hazard Ratio = 2. But what is log Relative Hazard ...
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1answer
34 views

Ideas and good practices for reporting crude survival trends?

I have 9-year-spanning data on patients survival (n = 10000). Each patient has a date of inclusion (got a diagnosis), which was used to determine the year of inclusion. Thus, temporal trends can be ...
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24 views

Which test should be used to compare crude mortality between 15 groups?

I have fifteen groups (factor levels) and I need to compare their crude mortality. Is Logrank test limited to two groups only? Which test would be correct to use in this case?
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1answer
205 views

Poisson regression for modeling standardized mortality ratio (SMR)

I have a data set with individuals with a certain diagnosis who are observed from the time of their diagnosis until death or the end date of the study. I want to calculate SMR for the whole group, and ...
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1answer
115 views

Is this a correct way to confirm Accelerated Failure Time (AFT) method's suitability for analysis? An example

I need to conduct an adjusted survival analysis, however, Cox PH assumption was not met and data stratification isn't a good solution as one of my study groups already has a small number of patients. ...
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68 views

Recent mortality [closed]

Recently there are a lot of datapoints regarding COVID-19 related deaths. However I am looking to see how big the impact of non-diagnosed patients is. Therefore I want to evaluate the deaths (...
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1answer
117 views

Is there a model to predict mortality rate of an ongoing epidemic?

Following the recent Coronavirus outbreak, various mortality rates have been published. Most of these are simply the ratio between the deaths and the total verified cases, which is not a very ...
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1answer
89 views

Estimate remaining time to failure based only on average time to failure

Suppose a random variable X representing time to failure. I don't know its pdf and only know its E[X]. How can I derive E[ X | X > t], i.e. average remaining time to failure? If it is impossible to do ...
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36 views

Cut off age for mortality data

I have data with death rates for each year 1921 to 2014; and for each age 0 to 110 as below: ...
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1answer
23 views

Representation of $l_x, d_x, L_x, T_x$

There are some problems in my textbook where a life table is given, with some of the entries missing. Based on the given entries, I have to fill up the complete life table. Suppose it is given $l_0 = ...
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70 views

Can you use a multistate life table with a continuous variable?

I am reviewing an article and can't be too explicit about the data, but they are estimating life expectancy and also disease-free life expectancy using multistate tables. Their main predictor/...
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51 views

Lee Carter mortality model - OLS (SVD) estimators if errors are heteroscedastic

In the classical Lee-Carter model, central death rates are modelled as follows: $\log(m(x,t)) = a(x) + b(x)\kappa(t) +\varepsilon(x,t)$ for some $x=0,\ldots,\omega$ and $t=1,\ldots, T$ and where $a(...
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117 views

How do I calculate standard error for mortality experiment?

I ran an experiment looking if injuries affect the mortality of crabs over 50 days. How do I calculate the standard error for days when crabs died in relation to the percent mortality? Say I start ...
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2answers
133 views

Cox regression different results with different combinations of variables

I need help understanding how to use cox hazzard model to calculate risk of death in data from a cohort study. I have a set of data on physical activity and I want to do a cox regression on ...
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1answer
93 views

How to plot mortality at age curve using lifespan data

I have a table with the lifespan of multiple individuals from a species and would like to use this data to plot a mortality rate curve, similar to that shown in figure 1 of this study:https://www....
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110 views

R - matrix optimization problem (Lee-Carter with MLE parameters)

I am trying to reproduce one of models evolved on the base of Lee-Carter model by use of RStudio. Because I am still pretty fresh in this software, my question is not really sophisticated. Applying ...
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215 views

Comparison of extrapolated kaplan-meier survival curve with background mortality

For my research I am doing an health economic assessment of patients with a renal transplant. For my model I need to know their (yearly) mortality probability. My plan was to extrapolate survival data ...
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1answer
33 views

How do I determine if the difference between treatment and control is significant when they have different sample sizes?

I am currently performing a test in C. elegans mortality. In my extract and negative control, different sample sizes of worms (25-30 worms) were used due to the degree of difficulty of transferring ...
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62 views

Concept of Stationary Population

In stationary population, there can be different probabilities for death in a given year for different age groups but these probabilities don't change over time. So the probability a 28 year old will ...
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34 views

“Number of Persons” instead of “Number of Person-years” in Stationary Population [closed]

I have learnt that the life table function $_{n}L_x$ is the number of person-years lived by the cohort between ages $x$ and $x+n$. But for stationary population, $_{n}L_x$ is defined as the number ...
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1answer
23 views

Distinction between “Mid-year population” and “Number of people alive”

Suppose $D_i=$ Observed number of deaths in the age group $(x_i, x_{i+1})$, $P_i=$ Mid-year population for age group $(x_i, x_{i+1})$, $N_i=$ Number of people alive at $x_i$ among whom $d_i$ ...
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1answer
268 views

Probability Vs Rate

Suppose $_{n}q_x$ is the $\textbf{probability}$ of dying between age $x$ and $x+n$. And $_{n}M_x$ is the age-specific death $\textbf{rate}$ in the observed population in the interval $(x, x+n)$. The ...
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292 views

r - Poor model fit with StMoMo package on Human Mortality Database

I am fitting USA mortality data from Human Mortality Database (with data downloaded from here after registering for a free account https://www.mortality.org/cgi-bin/hmd/hmd_download.php) with the ...
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26 views

Mortality rates - can multiple (overlapping) categories with <20 events be combined?

I'm trying to track trends in alcohol/tobacco/drug related deaths for a small, rural county. I have some locally produced stats where they seem to just add the relatively few alcohol and drug related ...
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1answer
110 views

How to define the Lee-Carter model and its constrains in Bayesian setting

I'm running the Bayesian version of Lee-Carter model on jags, using rjags R package. Given a matrix of data $M$ such that $M_{x,t}=\log m_x(t)$ where $m_x(t)$ is ...
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1k views

Clarification on how to perform nested cross-validation

I'm currently trying to get lifetables for our population based on death and population counts. My first idea was to follow this paper methodology but after some discussions we are planning to use ...
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279 views

Survival distribution's parameter estimation in R with MLE [closed]

I have this life table, where: qx: the probability that someone aged exactly x will die before reaching age (x+1) dx: the number of people who die age x last birthday lx: the number of people who ...
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99 views

Convert “Alive” counts per replicate and time to survival data

I have a raw data set describing survival in groups of individuals over time, organized as follows: ...
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1answer
381 views

Converting annual to daily mortality rate

In one excel workbook I am working on right now, the annual mortality rate is given as 3.082% And the formula for calculating the daily mortality rate is 1-EXP(LN(1-[annual mortality rate]/365) Why ...
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94 views

Right-censored cash flows and survival analysis

I am doing survival analysis on a disability claims dataset - each row tells me how long a person has been on claim and whether they have gone off claim yet. Ultimately I am interested in predicting ...
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1answer
129 views

Calculating Expected Number of Deaths from Life Tables

Normally, if analysing cohort data, I would expand on time using the Lexis macro (if using SAS) and then calculate the expected number of deaths as the life table central mortality rate (mx) matched ...
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157 views

How can I compare two standard mortality ratios (SMRs)? [duplicate]

I have a population who I separated into three groups: low, medium, high exposure. I calculated the standard mortality ratios (SMRs) for each of this group using a standard population. One of my ...