> **Possible Duplicate:** > [How to compute significant interaction estimates when main effect is not significant?](https://stats.stackexchange.com/questions/28936/how-to-compute-significant-interaction-estimates-when-main-effect-is-not-signifi) <!-- End of automatically inserted text --> I am an applied linguist and I am modelling responses to a vocabulary test taken by second language learners of English; the aim is to test theoretical hypotheses regarding the relationship between the nature of the word and the likelihood of the learners’ knowing that word. The models I am using to explore the role of explanatory variables are the random item Item Response Theory model LLTM+e (see de Boeck et al. 2011; de Boeck 2008). These are created using the lmer function in the LME4 package in R and treat item and person responses as random. The estimates shown below are effectively like those from a binary logistic regression model, indicating the log-odds of a correct response on a word, given certain properties. Covariates relate to both item and person characteristics. The nature of my concern is actually a basic regression issue. I have found a significant interaction between ability grouping of the test taker (GRP; with two levels High and Low) and the length of the word in letters (LEN_L). As far as I can see the estimate of the fixed effects for the first model shows that (a) the lower level learners have an overall lower probability of giving a correct answer (b) that LEN_L does not provide a significant explanation across the pattern of responses for the whole test-taker population, and (c) a significant interaction between GRP and LEN_L indicates that the lower ability learners are less likely to give a correct answer for a longer word. This is in keeping with theory. However, when I model the data without including the main effect for LEN_L, I am not seeing a significant effect for either high or low groups as shown in Model 2. LEN_L does not show as significant if modelled without interaction with grp low (not shown). I feel that I am missing something obvious, but I cannot quite grasp what is happening. And my references have run dry on this particular issue and I am thinking myself around in circles about it. (NB: in my full model I have many other significant covariates, but this pattern holds true.) My query basically regards whether I should use Model 1, including the non-significant main effect, or whether my findings from Model 2 indicate that the finding is a little unstable. Any advice would be much appreciated! (I can post more details if necessary.) Karen Model 1 Fixed effects: Estimate Std. Error z value Pr(>|z|) (Intercept) 0.25244 0.83194 0.303 0.76156 grp low -2.09126 0.26406 -7.920 2.38e-15 *** LEN_L 0.02093 0.13062 0.160 0.87272 grp low:LEN_L -0.09185 0.03146 -2.919 0.00351 ** Model 2 Fixed effects: Estimate Std. Error z value Pr(>|z|) (Intercept) 0.25243 0.83194 0.303 0.762 grp low -2.09126 0.26406 -7.920 2.38e-15 *** grp high:LEN_L 0.02093 0.13062 0.160 0.873 grp low:LEN_L -0.07092 0.13202 -0.537 0.591 > De Boeck, P., Bakker, M., Zwitser, R., Nivard, M., Hofman, A., > Tuerlinckx, F. and Partchev, I. (2011) [The Estimation of Item > Response Models with the 'lmer' Function from the lme4 Package in > R][1]. Journal of Statistical Software (39:12) pp 1-28 [1]: http://www.jstatsoft.org/v39/i12/